Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man

Background and aims: Colchicum autumnale contains an alkaloid called colchicine, which blocks the cell division by inhibiting mitosis. This study investigated a patient who was poisoned with C. autumnale in Iran.Description: The patient was a 44-year-old man who came to the emergency poisoning ward...

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Autores principales:	Mitra Rahimi, Fatemeh Razavi, Mahtab Hajian, Amir Noyani
Formato:	article
Lenguaje:	EN
Publicado:	Shahrekord University of Medical Sciences 2020
Materias:	toxicology poisoning colchicinum emergency medicine case report Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9298e6e57e084cb5a7bc5ba9318ef128
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spelling	oai:doaj.org-article:9298e6e57e084cb5a7bc5ba9318ef1282021-11-13T05:12:33ZHerbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man2423-3579https://doaj.org/article/9298e6e57e084cb5a7bc5ba9318ef1282020-07-01T00:00:00Zhttp://herbmed.skums.ac.ir/article_245769_0b4316b0d0d3a2b3ffc6754e69f41c4e.pdfhttps://doaj.org/toc/2423-3579Background and aims: Colchicum autumnale contains an alkaloid called colchicine, which blocks the cell division by inhibiting mitosis. This study investigated a patient who was poisoned with C. autumnale in Iran.Description: The patient was a 44-year-old man who came to the emergency poisoning ward after a day of hiking and eating soup. He presented with severe nausea and vomiting. The patient was admitted to the ICU two days later with general toxic conditions, complaining of chest pain, nausea, vomiting and shortness of breath. The laboratory tests showed elevated liver enzymes and pancytopenia. He developed respiratory distress and physician had to intubate him. He was treated with antibiotics, GCSF for pancytopenia and antioxidant to protect the liver.Conclusion: The patient responded to broad spectrum antibiotic, antifungal and GCSF. Paying attention to the patient’s history was the key to appropriate diagnosisMitra RahimiFatemeh RazaviMahtab HajianAmir NoyaniShahrekord University of Medical Sciencesarticletoxicologypoisoningcolchicinumemergency medicinecase reportMedicineRScienceQENAdvanced Herbal Medicine , Vol 6, Iss 2, Pp 75-79 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	toxicology poisoning colchicinum emergency medicine case report Medicine R Science Q
spellingShingle	toxicology poisoning colchicinum emergency medicine case report Medicine R Science Q Mitra Rahimi Fatemeh Razavi Mahtab Hajian Amir Noyani Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man
description	Background and aims: Colchicum autumnale contains an alkaloid called colchicine, which blocks the cell division by inhibiting mitosis. This study investigated a patient who was poisoned with C. autumnale in Iran.Description: The patient was a 44-year-old man who came to the emergency poisoning ward after a day of hiking and eating soup. He presented with severe nausea and vomiting. The patient was admitted to the ICU two days later with general toxic conditions, complaining of chest pain, nausea, vomiting and shortness of breath. The laboratory tests showed elevated liver enzymes and pancytopenia. He developed respiratory distress and physician had to intubate him. He was treated with antibiotics, GCSF for pancytopenia and antioxidant to protect the liver.Conclusion: The patient responded to broad spectrum antibiotic, antifungal and GCSF. Paying attention to the patient’s history was the key to appropriate diagnosis
format	article
author	Mitra Rahimi Fatemeh Razavi Mahtab Hajian Amir Noyani
author_facet	Mitra Rahimi Fatemeh Razavi Mahtab Hajian Amir Noyani
author_sort	Mitra Rahimi
title	Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man
title_short	Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man
title_full	Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man
title_fullStr	Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man
title_full_unstemmed	Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man
title_sort	herbal toxicity: a case report of toxicity with colchicum autumnale in a 44-year-old man
publisher	Shahrekord University of Medical Sciences
publishDate	2020
url	https://doaj.org/article/9298e6e57e084cb5a7bc5ba9318ef128
work_keys_str_mv	AT mitrarahimi herbaltoxicityacasereportoftoxicitywithcolchicumautumnaleina44yearoldman AT fatemehrazavi herbaltoxicityacasereportoftoxicitywithcolchicumautumnaleina44yearoldman AT mahtabhajian herbaltoxicityacasereportoftoxicitywithcolchicumautumnaleina44yearoldman AT amirnoyani herbaltoxicityacasereportoftoxicitywithcolchicumautumnaleina44yearoldman
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Herbal toxicity: A case report of toxicity with Colchicum autumnale in a 44-year-old man

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