An accurate and robust imputation method scImpute for single-cell RNA-seq data

Despite being widely performed in exploring cell heterogeneity and gene expression stochasticity, single cell RNA-seq analysis is complicated by excess zero counts (dropouts). Here, Li and Li develop scImpute for statistical imputation of dropouts in scRNA-seq data.

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Detalles Bibliográficos
Autores principales:	Wei Vivian Li, Jingyi Jessica Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/929c4a6aa64242ada152b435bb8e17f0
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spelling	oai:doaj.org-article:929c4a6aa64242ada152b435bb8e17f02021-12-02T14:41:28ZAn accurate and robust imputation method scImpute for single-cell RNA-seq data10.1038/s41467-018-03405-72041-1723https://doaj.org/article/929c4a6aa64242ada152b435bb8e17f02018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03405-7https://doaj.org/toc/2041-1723Despite being widely performed in exploring cell heterogeneity and gene expression stochasticity, single cell RNA-seq analysis is complicated by excess zero counts (dropouts). Here, Li and Li develop scImpute for statistical imputation of dropouts in scRNA-seq data.Wei Vivian LiJingyi Jessica LiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Vivian Li Jingyi Jessica Li An accurate and robust imputation method scImpute for single-cell RNA-seq data
description	Despite being widely performed in exploring cell heterogeneity and gene expression stochasticity, single cell RNA-seq analysis is complicated by excess zero counts (dropouts). Here, Li and Li develop scImpute for statistical imputation of dropouts in scRNA-seq data.
format	article
author	Wei Vivian Li Jingyi Jessica Li
author_facet	Wei Vivian Li Jingyi Jessica Li
author_sort	Wei Vivian Li
title	An accurate and robust imputation method scImpute for single-cell RNA-seq data
title_short	An accurate and robust imputation method scImpute for single-cell RNA-seq data
title_full	An accurate and robust imputation method scImpute for single-cell RNA-seq data
title_fullStr	An accurate and robust imputation method scImpute for single-cell RNA-seq data
title_full_unstemmed	An accurate and robust imputation method scImpute for single-cell RNA-seq data
title_sort	accurate and robust imputation method scimpute for single-cell rna-seq data
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/929c4a6aa64242ada152b435bb8e17f0
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An accurate and robust imputation method scImpute for single-cell RNA-seq data

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