An accurate and robust imputation method scImpute for single-cell RNA-seq data

Despite being widely performed in exploring cell heterogeneity and gene expression stochasticity, single cell RNA-seq analysis is complicated by excess zero counts (dropouts). Here, Li and Li develop scImpute for statistical imputation of dropouts in scRNA-seq data.

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Detalles Bibliográficos
Autores principales: Wei Vivian Li, Jingyi Jessica Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/929c4a6aa64242ada152b435bb8e17f0
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