X-ray structure of a carpet-like antimicrobial defensin–phospholipid membrane disruption complex

Defensins are cationic antimicrobial peptides that permeabilize membranes of pathogens presumably via the assembly of defensin–lipid oligomers. Here authors provide evidence for this by solving the crystal structure of a plant defensin in an oligomeric state with phospholipids.

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Autores principales: Michael Järvå, Fung T. Lay, Thanh Kha Phan, Cassandra Humble, Ivan K. H. Poon, Mark R. Bleackley, Marilyn A. Anderson, Mark D. Hulett, Marc Kvansakul
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/92a541026fb04b6bafa9a12c66ec4740
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