4-HIL mitigates type-2 diabetic complications through inhibiting inflammation and Nrf2 mediated oxidative stress in rats

4-HIL mitigates type-2 diabetic complications through inhibiting inflammation and Nrf2 mediated oxidative stress in rats

Background: Hyperglycemia induced diabetic complications as well as dysfunction of multiple organs is closely related to the increased inflammation and oxidative stress (OS). 4-hydroxyisoleucine (4-HIL), a major constituent of Trigonella foenum-graecum L. shown to have anti-diabetic effects. However...

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Bibliographic Details
Main Authors: Rupali Singh, Karan Singh Yadav, Ramanand Prajapati, Sharad Sharma, Srikanta Kumar Rath, Tadigoppula Narender, Madhav Nilakanth Mugale
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
4-hydroxyisoleucine
Antioxidant
Diabetic complication
Inflammation
Oxidative stress
Other systems of medicine
RZ201-999
Online Access:https://doaj.org/article/92ae82f14bdc4bdb98125d9cb29c2586
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https://doaj.org/article/92ae82f14bdc4bdb98125d9cb29c2586

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