Clinical utility of metabolic syndrome severity scores: considerations for practitioners

Mark D DeBoer,1,2 Matthew J Gurka2 11Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, 2Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA Abstract: The metabolic synd...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: DeBoer MD, Gurka MJ
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://doaj.org/article/92b82680b72547029458e71b5171b8a0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:92b82680b72547029458e71b5171b8a0
record_format dspace
spelling oai:doaj.org-article:92b82680b72547029458e71b5171b8a02021-12-02T02:37:23ZClinical utility of metabolic syndrome severity scores: considerations for practitioners1178-7007https://doaj.org/article/92b82680b72547029458e71b5171b8a02017-02-01T00:00:00Zhttps://www.dovepress.com/clinical-utility-of-metabolic-syndrome-severity-scores-considerations--peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Mark D DeBoer,1,2 Matthew J Gurka2 11Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, 2Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA Abstract: The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetS-related risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time. Keywords: metabolic syndrome, insulin resistance, cardiovascular disease, type 2 diabetes, risk predictionDeBoer MDGurka MJDove Medical Pressarticlemetabolic syndromeinsulin resistancecardiovascular diseasetype 2 diabetesrisk predictionSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 10, Pp 65-72 (2017)
institution DOAJ
collection DOAJ
language EN
topic metabolic syndrome
insulin resistance
cardiovascular disease
type 2 diabetes
risk prediction
Specialties of internal medicine
RC581-951
spellingShingle metabolic syndrome
insulin resistance
cardiovascular disease
type 2 diabetes
risk prediction
Specialties of internal medicine
RC581-951
DeBoer MD
Gurka MJ
Clinical utility of metabolic syndrome severity scores: considerations for practitioners
description Mark D DeBoer,1,2 Matthew J Gurka2 11Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, 2Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA Abstract: The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetS-related risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time. Keywords: metabolic syndrome, insulin resistance, cardiovascular disease, type 2 diabetes, risk prediction
format article
author DeBoer MD
Gurka MJ
author_facet DeBoer MD
Gurka MJ
author_sort DeBoer MD
title Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_short Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_full Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_fullStr Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_full_unstemmed Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_sort clinical utility of metabolic syndrome severity scores: considerations for practitioners
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/92b82680b72547029458e71b5171b8a0
work_keys_str_mv AT deboermd clinicalutilityofmetabolicsyndromeseverityscoresconsiderationsforpractitioners
AT gurkamj clinicalutilityofmetabolicsyndromeseverityscoresconsiderationsforpractitioners
_version_ 1718402303973654528