Clinical utility of metabolic syndrome severity scores: considerations for practitioners

Mark D DeBoer,1,2 Matthew J Gurka2 11Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, 2Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA Abstract: The metabolic synd...

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Main Authors:	DeBoer MD, Gurka MJ
Format:	article
Language:	EN
Published:	Dove Medical Press 2017
Subjects:	metabolic syndrome insulin resistance cardiovascular disease type 2 diabetes risk prediction Specialties of internal medicine RC581-951
Online Access:	https://doaj.org/article/92b82680b72547029458e71b5171b8a0
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spelling	oai:doaj.org-article:92b82680b72547029458e71b5171b8a02021-12-02T02:37:23ZClinical utility of metabolic syndrome severity scores: considerations for practitioners1178-7007https://doaj.org/article/92b82680b72547029458e71b5171b8a02017-02-01T00:00:00Zhttps://www.dovepress.com/clinical-utility-of-metabolic-syndrome-severity-scores-considerations--peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Mark D DeBoer,1,2 Matthew J Gurka2 11Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, 2Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA Abstract: The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetS-related risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time. Keywords: metabolic syndrome, insulin resistance, cardiovascular disease, type 2 diabetes, risk predictionDeBoer MDGurka MJDove Medical Pressarticlemetabolic syndromeinsulin resistancecardiovascular diseasetype 2 diabetesrisk predictionSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 10, Pp 65-72 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	metabolic syndrome insulin resistance cardiovascular disease type 2 diabetes risk prediction Specialties of internal medicine RC581-951
spellingShingle	metabolic syndrome insulin resistance cardiovascular disease type 2 diabetes risk prediction Specialties of internal medicine RC581-951 DeBoer MD Gurka MJ Clinical utility of metabolic syndrome severity scores: considerations for practitioners
description	Mark D DeBoer,1,2 Matthew J Gurka2 11Division of Pediatric Endocrinology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, 2Department of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA Abstract: The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetS-related risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time. Keywords: metabolic syndrome, insulin resistance, cardiovascular disease, type 2 diabetes, risk prediction
format	article
author	DeBoer MD Gurka MJ
author_facet	DeBoer MD Gurka MJ
author_sort	DeBoer MD
title	Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_short	Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_full	Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_fullStr	Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_full_unstemmed	Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_sort	clinical utility of metabolic syndrome severity scores: considerations for practitioners
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/92b82680b72547029458e71b5171b8a0
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Clinical utility of metabolic syndrome severity scores: considerations for practitioners

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