Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions

Background: During the transition period in dairy cows, metabolic changes occur, many of them related to energy metabolism, which causes metabolic diseases or productive alterations. Aim: The objective of the present work was to evaluate two mineral and vitamin supplementation related to metabolic...

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Autores principales:	Katherine García Alegría, Rómulo Campos Gaona, Mauricio Vélez Terranova, Erika Andrea Hernández
Formato:	article
Lenguaje:	EN
Publicado:	Tripoli University 2021
Materias:	insulin resistance transition period dairy cows metabolism nutrition factors Zoology QL1-991
Acceso en línea:	https://doaj.org/article/92b8cb70b81340f1b0776738a4688353
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spelling	oai:doaj.org-article:92b8cb70b81340f1b0776738a46883532021-11-09T22:05:08ZInsulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions10.5455/OVJ.2021.v11.i4.82226-44852218-6050https://doaj.org/article/92b8cb70b81340f1b0776738a46883532021-11-01T00:00:00Zhttps://www.openveterinaryjournal.com/OVJ-2021-08-149%20K.G.%20Alegria%20et%20al.pdfhttps://doaj.org/toc/2226-4485https://doaj.org/toc/2218-6050Background: During the transition period in dairy cows, metabolic changes occur, many of them related to energy metabolism, which causes metabolic diseases or productive alterations. Aim: The objective of the present work was to evaluate two mineral and vitamin supplementation related to metabolic regulation mechanisms associated with insulin during the transition period and the first phase of lactation in grazing cows under tropical conditions through metabolic indicators and insulin resistance indexes. Methods: Twenty-one animals were distributed in three groups, control (CTR), iodine supplementation (SUPP-1), and mixed mineral and vitamin supplementation (SUPP-2). The experimental period was from day 30 pre-partum to day 45 postpartum. The evaluation of body condition score and blood samples collection by coccygeal venipuncture was carried out for serum analysis of metabolites beta-hydroxybutyrate (BHB), glucose, and Non-Esterified Fatty Acids (NEFA) and the hormones insulin, thyroxine, triiodothyronine, and cortisol. Variables related to energy and hormone metabolism were analyzed. Four proposed indices were calculated to identify insulin resistance: HOMA, QUICKI, RQUICKI, and QUICKI-BHB. Through linear regression, the effect of metabolites and hormones on the indices of insulin resistance studied was estimated. Results: The groups with supplementation did not show significant changes in the mobilization of body reserves, NEFA, nor triiodothyronine for interaction between treatments and periods. HOMA and QUICKI indices used to estimate insulin resistance showed an inverse correlation (-0.97; p<0.001), and a greater capacity of linear adjustment to estimate the evaluated metabolites. Conclusions: The indexes values of insulin sensitivity in the present work constitute a starting point in tropical dairy cows to characterize insulin resistance and metabolic alterations. Vitamins and mineral supplementation did not show a positive effect on the metabolism of dairy cows during the transition period and the first phase of lactation in the study.Katherine García AlegríaRómulo Campos GaonaMauricio Vélez TerranovaErika Andrea HernándezTripoli Universityarticleinsulin resistancetransition perioddairy cowsmetabolismnutrition factorsZoologyQL1-991ENOpen Veterinary Journal, Vol 11, Iss 4, Pp 587-597 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	insulin resistance transition period dairy cows metabolism nutrition factors Zoology QL1-991
spellingShingle	insulin resistance transition period dairy cows metabolism nutrition factors Zoology QL1-991 Katherine García Alegría Rómulo Campos Gaona Mauricio Vélez Terranova Erika Andrea Hernández Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
description	Background: During the transition period in dairy cows, metabolic changes occur, many of them related to energy metabolism, which causes metabolic diseases or productive alterations. Aim: The objective of the present work was to evaluate two mineral and vitamin supplementation related to metabolic regulation mechanisms associated with insulin during the transition period and the first phase of lactation in grazing cows under tropical conditions through metabolic indicators and insulin resistance indexes. Methods: Twenty-one animals were distributed in three groups, control (CTR), iodine supplementation (SUPP-1), and mixed mineral and vitamin supplementation (SUPP-2). The experimental period was from day 30 pre-partum to day 45 postpartum. The evaluation of body condition score and blood samples collection by coccygeal venipuncture was carried out for serum analysis of metabolites beta-hydroxybutyrate (BHB), glucose, and Non-Esterified Fatty Acids (NEFA) and the hormones insulin, thyroxine, triiodothyronine, and cortisol. Variables related to energy and hormone metabolism were analyzed. Four proposed indices were calculated to identify insulin resistance: HOMA, QUICKI, RQUICKI, and QUICKI-BHB. Through linear regression, the effect of metabolites and hormones on the indices of insulin resistance studied was estimated. Results: The groups with supplementation did not show significant changes in the mobilization of body reserves, NEFA, nor triiodothyronine for interaction between treatments and periods. HOMA and QUICKI indices used to estimate insulin resistance showed an inverse correlation (-0.97; p<0.001), and a greater capacity of linear adjustment to estimate the evaluated metabolites. Conclusions: The indexes values of insulin sensitivity in the present work constitute a starting point in tropical dairy cows to characterize insulin resistance and metabolic alterations. Vitamins and mineral supplementation did not show a positive effect on the metabolism of dairy cows during the transition period and the first phase of lactation in the study.
format	article
author	Katherine García Alegría Rómulo Campos Gaona Mauricio Vélez Terranova Erika Andrea Hernández
author_facet	Katherine García Alegría Rómulo Campos Gaona Mauricio Vélez Terranova Erika Andrea Hernández
author_sort	Katherine García Alegría
title	Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
title_short	Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
title_full	Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
title_fullStr	Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
title_full_unstemmed	Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
title_sort	insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions
publisher	Tripoli University
publishDate	2021
url	https://doaj.org/article/92b8cb70b81340f1b0776738a4688353
work_keys_str_mv	AT katherinegarciaalegria insulinresistanceindexesofgrazingcowsandmineralorvitaminsupplementationundertropicalconditions AT romulocamposgaona insulinresistanceindexesofgrazingcowsandmineralorvitaminsupplementationundertropicalconditions AT mauriciovelezterranova insulinresistanceindexesofgrazingcowsandmineralorvitaminsupplementationundertropicalconditions AT erikaandreahernandez insulinresistanceindexesofgrazingcowsandmineralorvitaminsupplementationundertropicalconditions
_version_	1718440768602898432

Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions

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