DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS

Distribution of genotypes of biochemical markers of HP, GC, EsD, АсР genes, genotypes on polymorphic variants of the genes coding enzymes of biotransformation GSTT1 (GST-ɵ1) and GSTM1 (GST-μ1) and NOS3 (VNTR4 polymorphism) in the miners with chronic mechanic bronchitis, and in persons without this o...

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Autores principales: V. V. Zakharenkov, N. I. Gafarov, N. I. Panev, A. N. Kucher, M. B. Freydin, A. A. Rudko, T. K. Yadikina, A. S. Kazitskaya
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Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/92ba95716035416785d7badc97960585
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spelling oai:doaj.org-article:92ba95716035416785d7badc979605852021-11-23T06:14:17ZDISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS2541-94202587-9596https://doaj.org/article/92ba95716035416785d7badc979605852012-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/758https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Distribution of genotypes of biochemical markers of HP, GC, EsD, АсР genes, genotypes on polymorphic variants of the genes coding enzymes of biotransformation GSTT1 (GST-ɵ1) and GSTM1 (GST-μ1) and NOS3 (VNTR4 polymorphism) in the miners with chronic mechanic bronchitis, and in persons without this occupational pathology is investigated. It is shown that the owners of EsD 1-2, АсР bb genotypes are most subject to development of chronic mechanic bronchitis. Endogen factors of resistance to this disease are GC 1-1, EsD 1-1, АсР bc genotypes.V. V. ZakharenkovN. I. GafarovN. I. PanevA. N. KucherM. B. FreydinA. A. RudkoT. K. YadikinaA. S. KazitskayaScientific Сentre for Family Health and Human Reproduction Problemsarticlegenetic markersa genotypegenetic predispositionresistanceScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 93-97 (2012)
institution DOAJ
collection DOAJ
language RU
topic genetic markers
a genotype
genetic predisposition
resistance
Science
Q
spellingShingle genetic markers
a genotype
genetic predisposition
resistance
Science
Q
V. V. Zakharenkov
N. I. Gafarov
N. I. Panev
A. N. Kucher
M. B. Freydin
A. A. Rudko
T. K. Yadikina
A. S. Kazitskaya
DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
description Distribution of genotypes of biochemical markers of HP, GC, EsD, АсР genes, genotypes on polymorphic variants of the genes coding enzymes of biotransformation GSTT1 (GST-ɵ1) and GSTM1 (GST-μ1) and NOS3 (VNTR4 polymorphism) in the miners with chronic mechanic bronchitis, and in persons without this occupational pathology is investigated. It is shown that the owners of EsD 1-2, АсР bb genotypes are most subject to development of chronic mechanic bronchitis. Endogen factors of resistance to this disease are GC 1-1, EsD 1-1, АсР bc genotypes.
format article
author V. V. Zakharenkov
N. I. Gafarov
N. I. Panev
A. N. Kucher
M. B. Freydin
A. A. Rudko
T. K. Yadikina
A. S. Kazitskaya
author_facet V. V. Zakharenkov
N. I. Gafarov
N. I. Panev
A. N. Kucher
M. B. Freydin
A. A. Rudko
T. K. Yadikina
A. S. Kazitskaya
author_sort V. V. Zakharenkov
title DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
title_short DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
title_full DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
title_fullStr DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
title_full_unstemmed DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
title_sort distribution of biochemical and molecular-genetic markers of genes in workers of coal mining enterprises of kuzbass region suffering from chronic dust bronchitis
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2012
url https://doaj.org/article/92ba95716035416785d7badc97960585
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