DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS
Distribution of genotypes of biochemical markers of HP, GC, EsD, АсР genes, genotypes on polymorphic variants of the genes coding enzymes of biotransformation GSTT1 (GST-ɵ1) and GSTM1 (GST-μ1) and NOS3 (VNTR4 polymorphism) in the miners with chronic mechanic bronchitis, and in persons without this o...
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Scientific Сentre for Family Health and Human Reproduction Problems
2012
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oai:doaj.org-article:92ba95716035416785d7badc979605852021-11-23T06:14:17ZDISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS2541-94202587-9596https://doaj.org/article/92ba95716035416785d7badc979605852012-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/758https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Distribution of genotypes of biochemical markers of HP, GC, EsD, АсР genes, genotypes on polymorphic variants of the genes coding enzymes of biotransformation GSTT1 (GST-ɵ1) and GSTM1 (GST-μ1) and NOS3 (VNTR4 polymorphism) in the miners with chronic mechanic bronchitis, and in persons without this occupational pathology is investigated. It is shown that the owners of EsD 1-2, АсР bb genotypes are most subject to development of chronic mechanic bronchitis. Endogen factors of resistance to this disease are GC 1-1, EsD 1-1, АсР bc genotypes.V. V. ZakharenkovN. I. GafarovN. I. PanevA. N. KucherM. B. FreydinA. A. RudkoT. K. YadikinaA. S. KazitskayaScientific Сentre for Family Health and Human Reproduction Problemsarticlegenetic markersa genotypegenetic predispositionresistanceScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 93-97 (2012) |
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genetic markers a genotype genetic predisposition resistance Science Q |
spellingShingle |
genetic markers a genotype genetic predisposition resistance Science Q V. V. Zakharenkov N. I. Gafarov N. I. Panev A. N. Kucher M. B. Freydin A. A. Rudko T. K. Yadikina A. S. Kazitskaya DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS |
description |
Distribution of genotypes of biochemical markers of HP, GC, EsD, АсР genes, genotypes on polymorphic variants of the genes coding enzymes of biotransformation GSTT1 (GST-ɵ1) and GSTM1 (GST-μ1) and NOS3 (VNTR4 polymorphism) in the miners with chronic mechanic bronchitis, and in persons without this occupational pathology is investigated. It is shown that the owners of EsD 1-2, АсР bb genotypes are most subject to development of chronic mechanic bronchitis. Endogen factors of resistance to this disease are GC 1-1, EsD 1-1, АсР bc genotypes. |
format |
article |
author |
V. V. Zakharenkov N. I. Gafarov N. I. Panev A. N. Kucher M. B. Freydin A. A. Rudko T. K. Yadikina A. S. Kazitskaya |
author_facet |
V. V. Zakharenkov N. I. Gafarov N. I. Panev A. N. Kucher M. B. Freydin A. A. Rudko T. K. Yadikina A. S. Kazitskaya |
author_sort |
V. V. Zakharenkov |
title |
DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS |
title_short |
DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS |
title_full |
DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS |
title_fullStr |
DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS |
title_full_unstemmed |
DISTRIBUTION OF BIOCHEMICAL AND MOLECULAR-GENETIC MARKERS OF GENES IN WORKERS OF COAL MINING ENTERPRISES OF KUZBASS REGION SUFFERING FROM CHRONIC DUST BRONCHITIS |
title_sort |
distribution of biochemical and molecular-genetic markers of genes in workers of coal mining enterprises of kuzbass region suffering from chronic dust bronchitis |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2012 |
url |
https://doaj.org/article/92ba95716035416785d7badc97960585 |
work_keys_str_mv |
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