Heterochromatin is a quantitative trait associated with spontaneous epiallele formation

The molecular origins of epialleles remain unknown. Here, the authors show that a positive feedback loop between H3K9me2 and CMT2/3 is a major contributing factor to the origins of spontaneous epialleles and that heterochromatin is a quantitative trait associated with spontaneous epiallele formation...

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Main Authors:	Yinwen Zhang, Hosung Jang, Rui Xiao, Ioanna Kakoulidou, Robert S. Piecyk, Frank Johannes, Robert J. Schmitz
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/92bbdcf244a549d7bd6b64dcded0745b
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id	oai:doaj.org-article:92bbdcf244a549d7bd6b64dcded0745b
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spelling	oai:doaj.org-article:92bbdcf244a549d7bd6b64dcded0745b2021-12-05T12:22:32ZHeterochromatin is a quantitative trait associated with spontaneous epiallele formation10.1038/s41467-021-27320-62041-1723https://doaj.org/article/92bbdcf244a549d7bd6b64dcded0745b2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27320-6https://doaj.org/toc/2041-1723The molecular origins of epialleles remain unknown. Here, the authors show that a positive feedback loop between H3K9me2 and CMT2/3 is a major contributing factor to the origins of spontaneous epialleles and that heterochromatin is a quantitative trait associated with spontaneous epiallele formation.Yinwen ZhangHosung JangRui XiaoIoanna KakoulidouRobert S. PiecykFrank JohannesRobert J. SchmitzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yinwen Zhang Hosung Jang Rui Xiao Ioanna Kakoulidou Robert S. Piecyk Frank Johannes Robert J. Schmitz Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
description	The molecular origins of epialleles remain unknown. Here, the authors show that a positive feedback loop between H3K9me2 and CMT2/3 is a major contributing factor to the origins of spontaneous epialleles and that heterochromatin is a quantitative trait associated with spontaneous epiallele formation.
format	article
author	Yinwen Zhang Hosung Jang Rui Xiao Ioanna Kakoulidou Robert S. Piecyk Frank Johannes Robert J. Schmitz
author_facet	Yinwen Zhang Hosung Jang Rui Xiao Ioanna Kakoulidou Robert S. Piecyk Frank Johannes Robert J. Schmitz
author_sort	Yinwen Zhang
title	Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
title_short	Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
title_full	Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
title_fullStr	Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
title_full_unstemmed	Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
title_sort	heterochromatin is a quantitative trait associated with spontaneous epiallele formation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/92bbdcf244a549d7bd6b64dcded0745b
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Heterochromatin is a quantitative trait associated with spontaneous epiallele formation

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