Heterochromatin is a quantitative trait associated with spontaneous epiallele formation

The molecular origins of epialleles remain unknown. Here, the authors show that a positive feedback loop between H3K9me2 and CMT2/3 is a major contributing factor to the origins of spontaneous epialleles and that heterochromatin is a quantitative trait associated with spontaneous epiallele formation...

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Autores principales: Yinwen Zhang, Hosung Jang, Rui Xiao, Ioanna Kakoulidou, Robert S. Piecyk, Frank Johannes, Robert J. Schmitz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/92bbdcf244a549d7bd6b64dcded0745b
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