Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
The molecular origins of epialleles remain unknown. Here, the authors show that a positive feedback loop between H3K9me2 and CMT2/3 is a major contributing factor to the origins of spontaneous epialleles and that heterochromatin is a quantitative trait associated with spontaneous epiallele formation...
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Main Authors: | Yinwen Zhang, Hosung Jang, Rui Xiao, Ioanna Kakoulidou, Robert S. Piecyk, Frank Johannes, Robert J. Schmitz |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/92bbdcf244a549d7bd6b64dcded0745b |
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