Super-wide-field two-photon imaging with a micro-optical device moving in post-objective space

Recording the activity of neurons over large brain regions requires expanding the field of view of the optics without losing on spatial and temporal resolution. Here, the authors report a micro-opto-mechanical device that enables two-photon imaging across distant motor areas around 6 mm apart in the...

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Autores principales: Shin-Ichiro Terada, Kenta Kobayashi, Masamichi Ohkura, Junichi Nakai, Masanori Matsuzaki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/92c101dd3b0d4c3eaa6a3e419950508e
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Sumario:Recording the activity of neurons over large brain regions requires expanding the field of view of the optics without losing on spatial and temporal resolution. Here, the authors report a micro-opto-mechanical device that enables two-photon imaging across distant motor areas around 6 mm apart in the mouse.