The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis

Minh Tam Le,1,2 Nhu Quynh Thi Tran,1 Nguyen Dac Nguyen,1 Quoc Huy Vu Nguyen2 1Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam; 2Department of OBGYN, Hue University of Medicine and Pharmacy, Hue University, Hue, VietnamCorre...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Le MT, Tran NQT, Nguyen ND, Nguyen QHV
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	prevalence metabolic syndrome infertility sperm semen analysis Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/92c19b2506b4433ba5bf1994284b3141
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:92c19b2506b4433ba5bf1994284b3141
record_format	dspace
spelling	oai:doaj.org-article:92c19b2506b4433ba5bf1994284b31412021-12-02T15:59:21ZThe Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis1178-7007https://doaj.org/article/92c19b2506b4433ba5bf1994284b31412021-03-01T00:00:00Zhttps://www.dovepress.com/the-prevalence-and-components-of-metabolic-syndrome-in-men-from-infert-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Minh Tam Le,1,2 Nhu Quynh Thi Tran,1 Nguyen Dac Nguyen,1 Quoc Huy Vu Nguyen2 1Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam; 2Department of OBGYN, Hue University of Medicine and Pharmacy, Hue University, Hue, VietnamCorrespondence: Minh Tam LeCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, 06 Ngo Quyen Street, Hue, VietnamTel +84 989 228 779Fax +84 234 3822 173Email leminhtam@huemed-univ.edu.vnPurpose: Metabolic syndrome (MetS) has been reported as a deleterious factor in male fertility potential, associated with hypogonadism, impaired spermatogenesis, decreased sperm concentration and motility, and increased sperm DNA damage. This study aimed to determine the prevalence of MetS in men from infertile couples and evaluate its effect on semen analysis (SA).Participants and Methods: A cross-sectional descriptive study was performed in men from infertile couples diagnosed based on the World Health Organization 2010 criteria and treated at the Hue Center for Reproductive Endocrinology and Infertility, Vietnam. General information included medical history, lifestyle, MetS factors, SA, and sperm DNA fragmentation test were collected. Based on the diagnostic criteria of the American Heart Association and the National Heart, Lung, and Blood Institute for Asian men, the study population was divided into two groups: MetS and non-MetS groups. The outcomes were analyzed for any relationship between MetS and the SA index and the DNA fragmentation index (DFI).Results: A total of 534 men from infertile couples were included in this study. The prevalence of MetS was 23.4%, and abnormal semen analysis accounted for 93.8%. Age, body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), hepatitis B and total cholesterol were related to the occurrence of MetS in infertile men (p < 0.05). MetS did not reveal any impact on the parameters of SA. There was a positive correlation between waist circumference (WC), WHR, WHtR, and systolic blood pressure (BP) with abnormal sperm head and DFI (p < 0.05).Conclusion: Although the prevalence of MetS was remarkable in men from infertile couples, there was no association between MetS and semen quality. However, WC, WHR, WHtR, and systolic BP were found to be significantly associated with abnormal sperm head and DFI.Keywords: prevalence, metabolic syndrome, infertility, sperm, semen analysisLe MTTran NQTNguyen NDNguyen QHVDove Medical Pressarticleprevalencemetabolic syndromeinfertilityspermsemen analysisSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 1453-1463 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	prevalence metabolic syndrome infertility sperm semen analysis Specialties of internal medicine RC581-951
spellingShingle	prevalence metabolic syndrome infertility sperm semen analysis Specialties of internal medicine RC581-951 Le MT Tran NQT Nguyen ND Nguyen QHV The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis
description	Minh Tam Le,1,2 Nhu Quynh Thi Tran,1 Nguyen Dac Nguyen,1 Quoc Huy Vu Nguyen2 1Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam; 2Department of OBGYN, Hue University of Medicine and Pharmacy, Hue University, Hue, VietnamCorrespondence: Minh Tam LeCenter for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, 06 Ngo Quyen Street, Hue, VietnamTel +84 989 228 779Fax +84 234 3822 173Email leminhtam@huemed-univ.edu.vnPurpose: Metabolic syndrome (MetS) has been reported as a deleterious factor in male fertility potential, associated with hypogonadism, impaired spermatogenesis, decreased sperm concentration and motility, and increased sperm DNA damage. This study aimed to determine the prevalence of MetS in men from infertile couples and evaluate its effect on semen analysis (SA).Participants and Methods: A cross-sectional descriptive study was performed in men from infertile couples diagnosed based on the World Health Organization 2010 criteria and treated at the Hue Center for Reproductive Endocrinology and Infertility, Vietnam. General information included medical history, lifestyle, MetS factors, SA, and sperm DNA fragmentation test were collected. Based on the diagnostic criteria of the American Heart Association and the National Heart, Lung, and Blood Institute for Asian men, the study population was divided into two groups: MetS and non-MetS groups. The outcomes were analyzed for any relationship between MetS and the SA index and the DNA fragmentation index (DFI).Results: A total of 534 men from infertile couples were included in this study. The prevalence of MetS was 23.4%, and abnormal semen analysis accounted for 93.8%. Age, body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), hepatitis B and total cholesterol were related to the occurrence of MetS in infertile men (p < 0.05). MetS did not reveal any impact on the parameters of SA. There was a positive correlation between waist circumference (WC), WHR, WHtR, and systolic blood pressure (BP) with abnormal sperm head and DFI (p < 0.05).Conclusion: Although the prevalence of MetS was remarkable in men from infertile couples, there was no association between MetS and semen quality. However, WC, WHR, WHtR, and systolic BP were found to be significantly associated with abnormal sperm head and DFI.Keywords: prevalence, metabolic syndrome, infertility, sperm, semen analysis
format	article
author	Le MT Tran NQT Nguyen ND Nguyen QHV
author_facet	Le MT Tran NQT Nguyen ND Nguyen QHV
author_sort	Le MT
title	The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis
title_short	The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis
title_full	The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis
title_fullStr	The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis
title_full_unstemmed	The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis
title_sort	prevalence and components of metabolic syndrome in men from infertile couples and its relation on semen analysis
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/92c19b2506b4433ba5bf1994284b3141
work_keys_str_mv	AT lemt theprevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT trannqt theprevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT nguyennd theprevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT nguyenqhv theprevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT lemt prevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT trannqt prevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT nguyennd prevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis AT nguyenqhv prevalenceandcomponentsofmetabolicsyndromeinmenfrominfertilecouplesanditsrelationonsemenanalysis
_version_	1718385340864004096

The Prevalence and Components of Metabolic Syndrome in Men from Infertile Couples and Its Relation on Semen Analysis

Ejemplares similares