λ Phage nanobioparticle expressing apoptin efficiently suppress human breast carcinoma tumor growth in vivo.

λ Phage nanobioparticle expressing apoptin efficiently suppress human breast carcinoma tumor growth in vivo.

Using phages is a novel field of cancer therapy and phage nanobioparticles (NBPs) such as λ phage could be modified to deliver and express genetic cassettes into eukaryotic cells safely in contrast with animal viruses. Apoptin, a protein from chicken anemia virus (CAV) has the ability to specificall...

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Autores principales: Alireza Shoae-Hassani, Peyman Keyhanvar, Alexander Marcus Seifalian, Seyed Abdolreza Mortazavi-Tabatabaei, Narmin Ghaderi, Khosro Issazadeh, Nour Amirmozafari, Javad Verdi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/92cc5f32b1144f7c937647ea317acf76
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