An NO donor approach to neuroprotective and procognitive estrogen therapy overcomes loss of NO synthase function and potentially thrombotic risk.

Selective estrogen receptor modulators (SERMs) are effective therapeutics that preserve favorable actions of estrogens on bone and act as antiestrogens in breast tissue, decreasing the risk of vertebral fractures and breast cancer, but their potential in neuroprotective and procognitive therapy is l...

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Bibliographic Details
Main Authors: Lawren VandeVrede, Ramy Abdelhamid, Zhihui Qin, Jaewoo Choi, Sujeewa Piyankarage, Jia Luo, John Larson, Brian M Bennett, Gregory R J Thatcher
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/92d1a967b51f498891eff088417ce0b8
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