Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

SARS-CoV-2 has spread globally. Here, the authors characterize the entry pathway of SARS-CoV-2, show that the SARS-CoV-2 spike protein is less stable than that of SARS-CoV, and show limited cross-neutralization activities between SARS-CoV and SARS-CoV-2 sera.

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Autores principales:	Xiuyuan Ou, Yan Liu, Xiaobo Lei, Pei Li, Dan Mi, Lili Ren, Li Guo, Ruixuan Guo, Ting Chen, Jiaxin Hu, Zichun Xiang, Zhixia Mu, Xing Chen, Jieyong Chen, Keping Hu, Qi Jin, Jianwei Wang, Zhaohui Qian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/92d70903056e4689b4f7c4fd01947293
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spelling	oai:doaj.org-article:92d70903056e4689b4f7c4fd019472932021-12-02T17:31:09ZCharacterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV10.1038/s41467-020-15562-92041-1723https://doaj.org/article/92d70903056e4689b4f7c4fd019472932020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15562-9https://doaj.org/toc/2041-1723SARS-CoV-2 has spread globally. Here, the authors characterize the entry pathway of SARS-CoV-2, show that the SARS-CoV-2 spike protein is less stable than that of SARS-CoV, and show limited cross-neutralization activities between SARS-CoV and SARS-CoV-2 sera.Xiuyuan OuYan LiuXiaobo LeiPei LiDan MiLili RenLi GuoRuixuan GuoTing ChenJiaxin HuZichun XiangZhixia MuXing ChenJieyong ChenKeping HuQi JinJianwei WangZhaohui QianNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiuyuan Ou Yan Liu Xiaobo Lei Pei Li Dan Mi Lili Ren Li Guo Ruixuan Guo Ting Chen Jiaxin Hu Zichun Xiang Zhixia Mu Xing Chen Jieyong Chen Keping Hu Qi Jin Jianwei Wang Zhaohui Qian Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
description	SARS-CoV-2 has spread globally. Here, the authors characterize the entry pathway of SARS-CoV-2, show that the SARS-CoV-2 spike protein is less stable than that of SARS-CoV, and show limited cross-neutralization activities between SARS-CoV and SARS-CoV-2 sera.
format	article
author	Xiuyuan Ou Yan Liu Xiaobo Lei Pei Li Dan Mi Lili Ren Li Guo Ruixuan Guo Ting Chen Jiaxin Hu Zichun Xiang Zhixia Mu Xing Chen Jieyong Chen Keping Hu Qi Jin Jianwei Wang Zhaohui Qian
author_facet	Xiuyuan Ou Yan Liu Xiaobo Lei Pei Li Dan Mi Lili Ren Li Guo Ruixuan Guo Ting Chen Jiaxin Hu Zichun Xiang Zhixia Mu Xing Chen Jieyong Chen Keping Hu Qi Jin Jianwei Wang Zhaohui Qian
author_sort	Xiuyuan Ou
title	Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
title_short	Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
title_full	Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
title_fullStr	Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
title_full_unstemmed	Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
title_sort	characterization of spike glycoprotein of sars-cov-2 on virus entry and its immune cross-reactivity with sars-cov
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/92d70903056e4689b4f7c4fd01947293
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Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

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