Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.

Lean-type Pekin duck is a commercial breed that has been obtained through long-term selection. Investigation of the differentially expressed genes in breast muscle and skin fat at different developmental stages will contribute to a comprehensive understanding of the potential mechanisms underlying t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tieshan Xu, Lihong Gu, Kyle Michael Schachtschneider, Xiaolin Liu, Wei Huang, Ming Xie, Shuisheng Hou
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/92eb89c2944a4fd8865772b6cdce4c05
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:92eb89c2944a4fd8865772b6cdce4c05
record_format	dspace
spelling	oai:doaj.org-article:92eb89c2944a4fd8865772b6cdce4c052021-11-25T05:59:00ZIdentification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.1932-620310.1371/journal.pone.0107574https://doaj.org/article/92eb89c2944a4fd8865772b6cdce4c052014-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0107574https://doaj.org/toc/1932-6203Lean-type Pekin duck is a commercial breed that has been obtained through long-term selection. Investigation of the differentially expressed genes in breast muscle and skin fat at different developmental stages will contribute to a comprehensive understanding of the potential mechanisms underlying the lean-type Pekin duck phenotype. In the present study, RNA-seq was performed on breast muscle and skin fat at 2-, 4- and 6-weeks of age. More than 89% of the annotated duck genes were covered by our RNA-seq dataset. Thousands of differentially expressed genes, including many important genes involved in the regulation of muscle development and fat deposition, were detected through comparison of the expression levels in the muscle and skin fat of the same time point, or the same tissue at different time points. KEGG pathway analysis showed that the differentially expressed genes clustered significantly in many muscle development and fat deposition related pathways such as MAPK signaling pathway, PPAR signaling pathway, Calcium signaling pathway, Fat digestion and absorption, and TGF-beta signaling pathway. The results presented here could provide a basis for further investigation of the mechanisms involved in muscle development and fat deposition in Pekin duck.Tieshan XuLihong GuKyle Michael SchachtschneiderXiaolin LiuWei HuangMing XieShuisheng HouPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 9, p e107574 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tieshan Xu Lihong Gu Kyle Michael Schachtschneider Xiaolin Liu Wei Huang Ming Xie Shuisheng Hou Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.
description	Lean-type Pekin duck is a commercial breed that has been obtained through long-term selection. Investigation of the differentially expressed genes in breast muscle and skin fat at different developmental stages will contribute to a comprehensive understanding of the potential mechanisms underlying the lean-type Pekin duck phenotype. In the present study, RNA-seq was performed on breast muscle and skin fat at 2-, 4- and 6-weeks of age. More than 89% of the annotated duck genes were covered by our RNA-seq dataset. Thousands of differentially expressed genes, including many important genes involved in the regulation of muscle development and fat deposition, were detected through comparison of the expression levels in the muscle and skin fat of the same time point, or the same tissue at different time points. KEGG pathway analysis showed that the differentially expressed genes clustered significantly in many muscle development and fat deposition related pathways such as MAPK signaling pathway, PPAR signaling pathway, Calcium signaling pathway, Fat digestion and absorption, and TGF-beta signaling pathway. The results presented here could provide a basis for further investigation of the mechanisms involved in muscle development and fat deposition in Pekin duck.
format	article
author	Tieshan Xu Lihong Gu Kyle Michael Schachtschneider Xiaolin Liu Wei Huang Ming Xie Shuisheng Hou
author_facet	Tieshan Xu Lihong Gu Kyle Michael Schachtschneider Xiaolin Liu Wei Huang Ming Xie Shuisheng Hou
author_sort	Tieshan Xu
title	Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.
title_short	Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.
title_full	Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.
title_fullStr	Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.
title_full_unstemmed	Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.
title_sort	identification of differentially expressed genes in breast muscle and skin fat of postnatal pekin duck.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/92eb89c2944a4fd8865772b6cdce4c05
work_keys_str_mv	AT tieshanxu identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck AT lihonggu identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck AT kylemichaelschachtschneider identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck AT xiaolinliu identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck AT weihuang identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck AT mingxie identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck AT shuishenghou identificationofdifferentiallyexpressedgenesinbreastmuscleandskinfatofpostnatalpekinduck
_version_	1718414355205193728

Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck.

Ejemplares similares