Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake.

Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake.

Ciliary neurotrophic factor (CNTF) is a potent neuroprotective cytokine in different animal models of glutamate-induced excitotoxicity, although its action mechanisms are still poorly characterized. We tested the hypothesis that an increased function of glial glutamate transporters (GTs) could under...

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Autores principales: Corinne Beurrier, Mathilde Faideau, Khaled-Ezaheir Bennouar, Carole Escartin, Lydia Kerkerian-Le Goff, Gilles Bonvento, Paolo Gubellini
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/92ed0c11fe5141daa8a890d2e8315783
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