Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake.

Ciliary neurotrophic factor (CNTF) is a potent neuroprotective cytokine in different animal models of glutamate-induced excitotoxicity, although its action mechanisms are still poorly characterized. We tested the hypothesis that an increased function of glial glutamate transporters (GTs) could under...

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Auteurs principaux: Corinne Beurrier, Mathilde Faideau, Khaled-Ezaheir Bennouar, Carole Escartin, Lydia Kerkerian-Le Goff, Gilles Bonvento, Paolo Gubellini
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/92ed0c11fe5141daa8a890d2e8315783
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