Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.

Hybrids between different inbred varieties display novel patterns of gene expression resulted from parental variation in allelic nucleotide sequences. To study the function of chromatin regulators in hybrid gene expression, the histone deacetylase gene OsHDT1 whose expression displayed a circadian r...

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Autores principales:	Chen Li, Limin Huang, Caiguo Xu, Yu Zhao, Dao-Xiu Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9304a29fd1b842939f99bf65cedcf2bb
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spelling	oai:doaj.org-article:9304a29fd1b842939f99bf65cedcf2bb2021-11-18T06:50:33ZAltered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.1932-620310.1371/journal.pone.0021789https://doaj.org/article/9304a29fd1b842939f99bf65cedcf2bb2011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21760907/?tool=EBIhttps://doaj.org/toc/1932-6203Hybrids between different inbred varieties display novel patterns of gene expression resulted from parental variation in allelic nucleotide sequences. To study the function of chromatin regulators in hybrid gene expression, the histone deacetylase gene OsHDT1 whose expression displayed a circadian rhythm was over-expressed or inactivated by RNAi in an elite rice parent. Increased OsHDT1 expression did not affect plant growth in the parent but led to early flowering in the hybrid. Nonadditive up-regulation of key flowering time genes was found to be related to flowering time of the hybrid. Over-expression of OsHDT1 repressed the nonadditive expression of the key flowering repressors in the hybrid (i.e. OsGI and Hd1) inducing early flowering. Analysis of histone acetylation suggested that OsHDT1 over-expression might promote deacetylation on OsGI and Hd1 chromatin during the peak expression phase. High throughput differential gene expression analysis revealed that altered OsHDT1 levels affected nonadditive expression of many genes in the hybrid. These data demonstrate that nonadditive gene expression was involved in flowering time control in the hybrid rice and that OsHDT1 level was important for nonadditive or differential expression of many genes including the flowering time genes, suggesting that OsHDT1 may be involved in epigenetic control of parental genome interaction for differential gene expression.Chen LiLimin HuangCaiguo XuYu ZhaoDao-Xiu ZhouPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 7, p e21789 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chen Li Limin Huang Caiguo Xu Yu Zhao Dao-Xiu Zhou Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
description	Hybrids between different inbred varieties display novel patterns of gene expression resulted from parental variation in allelic nucleotide sequences. To study the function of chromatin regulators in hybrid gene expression, the histone deacetylase gene OsHDT1 whose expression displayed a circadian rhythm was over-expressed or inactivated by RNAi in an elite rice parent. Increased OsHDT1 expression did not affect plant growth in the parent but led to early flowering in the hybrid. Nonadditive up-regulation of key flowering time genes was found to be related to flowering time of the hybrid. Over-expression of OsHDT1 repressed the nonadditive expression of the key flowering repressors in the hybrid (i.e. OsGI and Hd1) inducing early flowering. Analysis of histone acetylation suggested that OsHDT1 over-expression might promote deacetylation on OsGI and Hd1 chromatin during the peak expression phase. High throughput differential gene expression analysis revealed that altered OsHDT1 levels affected nonadditive expression of many genes in the hybrid. These data demonstrate that nonadditive gene expression was involved in flowering time control in the hybrid rice and that OsHDT1 level was important for nonadditive or differential expression of many genes including the flowering time genes, suggesting that OsHDT1 may be involved in epigenetic control of parental genome interaction for differential gene expression.
format	article
author	Chen Li Limin Huang Caiguo Xu Yu Zhao Dao-Xiu Zhou
author_facet	Chen Li Limin Huang Caiguo Xu Yu Zhao Dao-Xiu Zhou
author_sort	Chen Li
title	Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
title_short	Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
title_full	Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
title_fullStr	Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
title_full_unstemmed	Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
title_sort	altered levels of histone deacetylase oshdt1 affect differential gene expression patterns in hybrid rice.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/9304a29fd1b842939f99bf65cedcf2bb
work_keys_str_mv	AT chenli alteredlevelsofhistonedeacetylaseoshdt1affectdifferentialgeneexpressionpatternsinhybridrice AT liminhuang alteredlevelsofhistonedeacetylaseoshdt1affectdifferentialgeneexpressionpatternsinhybridrice AT caiguoxu alteredlevelsofhistonedeacetylaseoshdt1affectdifferentialgeneexpressionpatternsinhybridrice AT yuzhao alteredlevelsofhistonedeacetylaseoshdt1affectdifferentialgeneexpressionpatternsinhybridrice AT daoxiuzhou alteredlevelsofhistonedeacetylaseoshdt1affectdifferentialgeneexpressionpatternsinhybridrice
_version_	1718424307380518912

Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.

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