Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

Abstract Background Colistin is used against multi-drug resistant pathogens, yet resistance emerges through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes involved in lipopolysaccharide synthesis (i.e. mgrB, phoPQ, pmrCAB). Phenotypic susceptibility testing is challen...

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Bibliographic Details
Main Authors: Diana Albertos Torres, Helena M. B. Seth-Smith, Nicole Joosse, Claudia Lang, Olivier Dubuis, Magdalena Nüesch-Inderbinen, Vladimira Hinic, Adrian Egli
Format: article
Language:EN
Published: BMC 2021
Subjects:
Colistin
Resistance
Antimicrobial susceptibility testing
WGS
Antimicrobial resistance genes
Microbiology
QR1-502
Online Access:https://doaj.org/article/9304e7b785764422a07c56150e8fdb31
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https://doaj.org/article/9304e7b785764422a07c56150e8fdb31

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