Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

Alternative polyadenylation generates multiple mRNA isoforms with different 3′ UTR sizes. Here the authors report global 3′ UTR shortening that is coupled to increased expression of secretory pathway genes in secretory cell differentiation.

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Autores principales:	Larry C. Cheng, Dinghai Zheng, Erdene Baljinnyam, Fangzheng Sun, Koichi Ogami, Percy Luk Yeung, Mainul Hoque, Chi-Wei Lu, James L. Manley, Bin Tian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb2
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spelling	oai:doaj.org-article:930e44d8511440f79f4ea3c291ee5bb22021-12-02T18:02:52ZWidespread transcript shortening through alternative polyadenylation in secretory cell differentiation10.1038/s41467-020-16959-22041-1723https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb22020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16959-2https://doaj.org/toc/2041-1723Alternative polyadenylation generates multiple mRNA isoforms with different 3′ UTR sizes. Here the authors report global 3′ UTR shortening that is coupled to increased expression of secretory pathway genes in secretory cell differentiation.Larry C. ChengDinghai ZhengErdene BaljinnyamFangzheng SunKoichi OgamiPercy Luk YeungMainul HoqueChi-Wei LuJames L. ManleyBin TianNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Larry C. Cheng Dinghai Zheng Erdene Baljinnyam Fangzheng Sun Koichi Ogami Percy Luk Yeung Mainul Hoque Chi-Wei Lu James L. Manley Bin Tian Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
description	Alternative polyadenylation generates multiple mRNA isoforms with different 3′ UTR sizes. Here the authors report global 3′ UTR shortening that is coupled to increased expression of secretory pathway genes in secretory cell differentiation.
format	article
author	Larry C. Cheng Dinghai Zheng Erdene Baljinnyam Fangzheng Sun Koichi Ogami Percy Luk Yeung Mainul Hoque Chi-Wei Lu James L. Manley Bin Tian
author_facet	Larry C. Cheng Dinghai Zheng Erdene Baljinnyam Fangzheng Sun Koichi Ogami Percy Luk Yeung Mainul Hoque Chi-Wei Lu James L. Manley Bin Tian
author_sort	Larry C. Cheng
title	Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
title_short	Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
title_full	Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
title_fullStr	Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
title_full_unstemmed	Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
title_sort	widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb2
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Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

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