Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

Alternative polyadenylation generates multiple mRNA isoforms with different 3′ UTR sizes. Here the authors report global 3′ UTR shortening that is coupled to increased expression of secretory pathway genes in secretory cell differentiation.

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Autores principales: Larry C. Cheng, Dinghai Zheng, Erdene Baljinnyam, Fangzheng Sun, Koichi Ogami, Percy Luk Yeung, Mainul Hoque, Chi-Wei Lu, James L. Manley, Bin Tian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb2
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https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb2

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