Enzymatic enhancing of triplet–triplet annihilation upconversion by breaking oxygen quenching for background-free biological sensing

Triplet-triplet annihilation upconversion (TTA-UC) nanoparticles (NPs) are a promising material for diverse applications, but TTA-UC is sensitive to oxygen, which hinders its biological utility. Here, the authors report an enzymatic method to deplete oxygen and amplify the upconversion of TTA-UCNP i...

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Autores principales: Ling Huang, Timmy Le, Kai Huang, Gang Han
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9311c175e758406fb50362d115bec847
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Sumario:Triplet-triplet annihilation upconversion (TTA-UC) nanoparticles (NPs) are a promising material for diverse applications, but TTA-UC is sensitive to oxygen, which hinders its biological utility. Here, the authors report an enzymatic method to deplete oxygen and amplify the upconversion of TTA-UCNP in aqueous solution, and develop background-free glucose and glucose metabolism enzyme sensors.