Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions
The rat is a widely-used model for human biology, but we must be aware of metabolic differences. Here, the authors reconstruct the genome-scale metabolic network of the rat, and after reconciling it with an improved human metabolic model, demonstrate the power of the models to integrate toxicogenomi...
Guardado en:
Autores principales: | Edik M. Blais, Kristopher D. Rawls, Bonnie V. Dougherty, Zhuo I. Li, Glynis L. Kolling, Ping Ye, Anders Wallqvist, Jason A. Papin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9312236e6c4d45bfabd7e89d7160bf95 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures
por: Jill A. Franzosa, et al.
Publicado: (2021) -
Untargeted Metabolomics Reveals Species-Specific Metabolite Production and Shared Nutrient Consumption by Pseudomonas aeruginosa and Staphylococcus aureus
por: Laura J. Dunphy, et al.
Publicado: (2021) -
Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates
por: Johan Nyström-Persson, et al.
Publicado: (2017) -
Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials
por: Laura Aliisa Saarimäki, et al.
Publicado: (2021) -
Reconciling Rights and Obligations
por: Pernille Ironside
Publicado: (2003)