A unique Pd-catalysed Heck arylation as a remote trigger for cyclopropane selective ring-opening
Functionalizing multiple, distant sites across a molecule is a challenge. Here the authors report a remote functionalization strategy, whereby an initial Heck reaction leads to chain-walking of palladium across a molecule, ring-opening cyclopropanes while retaining the stereochemistry in the product...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/9319fac62c524a47a88a61dc8a81b806 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Functionalizing multiple, distant sites across a molecule is a challenge. Here the authors report a remote functionalization strategy, whereby an initial Heck reaction leads to chain-walking of palladium across a molecule, ring-opening cyclopropanes while retaining the stereochemistry in the product. |
|---|