Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Abstract Autoimmune hemolytic anemia (AIHA) is a potentially severe disease in which red blood cells (RBC) are destroyed by IgG anti-RBC autoantibodies which can lead to hemolysis. We recently found IgG Fc-glycosylation towards platelet and RBC alloantigens to be skewed towards decreased fucosylatio...

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Autores principales: Myrthe E. Sonneveld, Masja de Haas, Carolien Koeleman, Noortje de Haan, Sacha S. Zeerleder, Peter C. Ligthart, Manfred Wuhrer, C. Ellen van der Schoot, Gestur Vidarsson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/9331eca3284a4261ade0540383c4b35b
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