m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome

m6Am is a dynamic and reversible RNA modification found on the mRNA cap. Here the authors report m6Am-seq to directly distinguish m6Am from m6A and identify functional methylation sites.

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Autores principales: Hanxiao Sun, Kai Li, Xiaoting Zhang, Jun’e Liu, Meiling Zhang, Haowei Meng, Chengqi Yi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/933850ba218d4111a6de26367c71e82f
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spelling oai:doaj.org-article:933850ba218d4111a6de26367c71e82f2021-12-02T14:53:37Zm6Am-seq reveals the dynamic m6Am methylation in the human transcriptome10.1038/s41467-021-25105-52041-1723https://doaj.org/article/933850ba218d4111a6de26367c71e82f2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25105-5https://doaj.org/toc/2041-1723m6Am is a dynamic and reversible RNA modification found on the mRNA cap. Here the authors report m6Am-seq to directly distinguish m6Am from m6A and identify functional methylation sites.Hanxiao SunKai LiXiaoting ZhangJun’e LiuMeiling ZhangHaowei MengChengqi YiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hanxiao Sun
Kai Li
Xiaoting Zhang
Jun’e Liu
Meiling Zhang
Haowei Meng
Chengqi Yi
m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
description m6Am is a dynamic and reversible RNA modification found on the mRNA cap. Here the authors report m6Am-seq to directly distinguish m6Am from m6A and identify functional methylation sites.
format article
author Hanxiao Sun
Kai Li
Xiaoting Zhang
Jun’e Liu
Meiling Zhang
Haowei Meng
Chengqi Yi
author_facet Hanxiao Sun
Kai Li
Xiaoting Zhang
Jun’e Liu
Meiling Zhang
Haowei Meng
Chengqi Yi
author_sort Hanxiao Sun
title m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
title_short m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
title_full m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
title_fullStr m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
title_full_unstemmed m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
title_sort m6am-seq reveals the dynamic m6am methylation in the human transcriptome
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/933850ba218d4111a6de26367c71e82f
work_keys_str_mv AT hanxiaosun m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
AT kaili m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
AT xiaotingzhang m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
AT juneliu m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
AT meilingzhang m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
AT haoweimeng m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
AT chengqiyi m6amseqrevealsthedynamicm6ammethylationinthehumantranscriptome
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