Leveraging Immunopeptidomics To Study and Combat Infectious Disease

T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells...

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Autores principales:	Owen K. Leddy, Forest M. White, Bryan D. Bryson
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/933d0ab64c25497f97fe5f6157b51f9f
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spelling	oai:doaj.org-article:933d0ab64c25497f97fe5f6157b51f9f2021-12-02T19:42:55ZLeveraging Immunopeptidomics To Study and Combat Infectious Disease2379-507710.1128/mSystems.00310-21https://doaj.org/article/933d0ab64c25497f97fe5f6157b51f9f2021-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00310-21https://doaj.org/toc/2379-5077 T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells and professional antigen-presenting cells (APCs) during infection may therefore provide a route toward developing new vaccines.Owen K. LeddyForest M. WhiteBryan D. BrysonAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Owen K. Leddy Forest M. White Bryan D. Bryson Leveraging Immunopeptidomics To Study and Combat Infectious Disease
description	T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells and professional antigen-presenting cells (APCs) during infection may therefore provide a route toward developing new vaccines.
format	article
author	Owen K. Leddy Forest M. White Bryan D. Bryson
author_facet	Owen K. Leddy Forest M. White Bryan D. Bryson
author_sort	Owen K. Leddy
title	Leveraging Immunopeptidomics To Study and Combat Infectious Disease
title_short	Leveraging Immunopeptidomics To Study and Combat Infectious Disease
title_full	Leveraging Immunopeptidomics To Study and Combat Infectious Disease
title_fullStr	Leveraging Immunopeptidomics To Study and Combat Infectious Disease
title_full_unstemmed	Leveraging Immunopeptidomics To Study and Combat Infectious Disease
title_sort	leveraging immunopeptidomics to study and combat infectious disease
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/933d0ab64c25497f97fe5f6157b51f9f
work_keys_str_mv	AT owenkleddy leveragingimmunopeptidomicstostudyandcombatinfectiousdisease AT forestmwhite leveragingimmunopeptidomicstostudyandcombatinfectiousdisease AT bryandbryson leveragingimmunopeptidomicstostudyandcombatinfectiousdisease
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Leveraging Immunopeptidomics To Study and Combat Infectious Disease

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