EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING

Objective: To evaluate changes in visual acuity and contrast sensitivity in patients with keratoconus after corneal collagen cross-linking. Study Design: Quasi-experimental study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from May 2019 to Apr 2...

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Autores principales:	Hassaan Javaid, Omar Zafar, Seemal Akram, Asfandyar Khan, Sana Abbas, Aisha Rafique
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	corneal cross-linking keratoconus Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/933d9527c6524645bab3b5c468d21d84
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spelling	oai:doaj.org-article:933d9527c6524645bab3b5c468d21d842021-11-19T03:50:08ZEVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING0030-96482411-8842https://doaj.org/article/933d9527c6524645bab3b5c468d21d842021-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/4360/3604https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To evaluate changes in visual acuity and contrast sensitivity in patients with keratoconus after corneal collagen cross-linking. Study Design: Quasi-experimental study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from May 2019 to Apr 2020. Methodology: A total of 48 eyes of 30 patients with progressive keratoconus were included in this study. Baseline uncorrected distance visual acuity, corrected distance visual acuity and contrast sensitivity were recorded, following which transepithelial corneal collagen cross-linking with topical riboflavin and ultraviolet A light was performed. Uncorrected distance visual acuity, corrected distance visual acuity and contrast sensitivity measurements were repeated and recorded 6-months postoperatively. Results: Mean preoperative uncorrected distance visual acuity was 0.56 ± 0.27 logarithm of the minimum angle of resolution which improved to 0.51 ± 0.26 at 6 months after the procedure (p=0.002). Mean corrected distance visual acuity was 0.30 ± 0.19 preoperatively, improving to 0.24 ± 0.18 (p=0.001) at 6 months after corneal collagen cross-linking, thereby depicting a statistically significant improvement. Treated eyes also showed a significant improvement in contrast sensitivity (p=0.001) of 0.05 ± 0.08 logarithmic units of contrast sensitivity, from a mean preoperative contrast sensitivity of 1.72 ± 0.10 to 1.77 ± 0.09 when evaluated 6 months after corneal collagen cross-linking. Conclusion: Corneal collagen cross-linking is a promising advancement in the treatment of keratoconus. It was found effective in significantly improving visual acuity as well as contrast sensitivity, thus enhancing visual outcomes in keratoconus.Hassaan JavaidOmar ZafarSeemal AkramAsfandyar KhanSana AbbasAisha RafiqueArmy Medical College Rawalpindiarticlecorneal cross-linkingkeratoconusMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 5, Pp 1705-1708 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	corneal cross-linking keratoconus Medicine R Medicine (General) R5-920
spellingShingle	corneal cross-linking keratoconus Medicine R Medicine (General) R5-920 Hassaan Javaid Omar Zafar Seemal Akram Asfandyar Khan Sana Abbas Aisha Rafique EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING
description	Objective: To evaluate changes in visual acuity and contrast sensitivity in patients with keratoconus after corneal collagen cross-linking. Study Design: Quasi-experimental study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from May 2019 to Apr 2020. Methodology: A total of 48 eyes of 30 patients with progressive keratoconus were included in this study. Baseline uncorrected distance visual acuity, corrected distance visual acuity and contrast sensitivity were recorded, following which transepithelial corneal collagen cross-linking with topical riboflavin and ultraviolet A light was performed. Uncorrected distance visual acuity, corrected distance visual acuity and contrast sensitivity measurements were repeated and recorded 6-months postoperatively. Results: Mean preoperative uncorrected distance visual acuity was 0.56 ± 0.27 logarithm of the minimum angle of resolution which improved to 0.51 ± 0.26 at 6 months after the procedure (p=0.002). Mean corrected distance visual acuity was 0.30 ± 0.19 preoperatively, improving to 0.24 ± 0.18 (p=0.001) at 6 months after corneal collagen cross-linking, thereby depicting a statistically significant improvement. Treated eyes also showed a significant improvement in contrast sensitivity (p=0.001) of 0.05 ± 0.08 logarithmic units of contrast sensitivity, from a mean preoperative contrast sensitivity of 1.72 ± 0.10 to 1.77 ± 0.09 when evaluated 6 months after corneal collagen cross-linking. Conclusion: Corneal collagen cross-linking is a promising advancement in the treatment of keratoconus. It was found effective in significantly improving visual acuity as well as contrast sensitivity, thus enhancing visual outcomes in keratoconus.
format	article
author	Hassaan Javaid Omar Zafar Seemal Akram Asfandyar Khan Sana Abbas Aisha Rafique
author_facet	Hassaan Javaid Omar Zafar Seemal Akram Asfandyar Khan Sana Abbas Aisha Rafique
author_sort	Hassaan Javaid
title	EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING
title_short	EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING
title_full	EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING
title_fullStr	EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING
title_full_unstemmed	EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING
title_sort	evaluation of changes in visual acuity and contrast sensitivity in patients with keratoconus after corneal collagen cross-linking
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/933d9527c6524645bab3b5c468d21d84
work_keys_str_mv	AT hassaanjavaid evaluationofchangesinvisualacuityandcontrastsensitivityinpatientswithkeratoconusaftercornealcollagencrosslinking AT omarzafar evaluationofchangesinvisualacuityandcontrastsensitivityinpatientswithkeratoconusaftercornealcollagencrosslinking AT seemalakram evaluationofchangesinvisualacuityandcontrastsensitivityinpatientswithkeratoconusaftercornealcollagencrosslinking AT asfandyarkhan evaluationofchangesinvisualacuityandcontrastsensitivityinpatientswithkeratoconusaftercornealcollagencrosslinking AT sanaabbas evaluationofchangesinvisualacuityandcontrastsensitivityinpatientswithkeratoconusaftercornealcollagencrosslinking AT aisharafique evaluationofchangesinvisualacuityandcontrastsensitivityinpatientswithkeratoconusaftercornealcollagencrosslinking
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EVALUATION OF CHANGES IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH KERATOCONUS AFTER CORNEAL COLLAGEN CROSS-LINKING

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