CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS

Abstract. We have studied effects of UV irradiation (240-390 nm) at a dose range of 151 to 1359 J/m2 upon expression levels of different surface markers (CD2, CD11a, CD3, CD4, CD8) of human blood T lymphocytes by means of laser flow cytofluorimetry. It is revealed that UV-irradiation at the doses of...

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Autores principales:	V. G. Artuykhov, O. V. Putintseva, S. M. Dubova, V. A. Bragina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	expression adhesion molecules cd3 cd4 cd8 markers uv-light Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/933f53445f7f4cf785920f55bdae2e26
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spelling	oai:doaj.org-article:933f53445f7f4cf785920f55bdae2e262021-11-18T08:03:43ZCHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS1563-06252313-741X10.15789/1563-0625-2013-4-361-368https://doaj.org/article/933f53445f7f4cf785920f55bdae2e262014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/647https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We have studied effects of UV irradiation (240-390 nm) at a dose range of 151 to 1359 J/m2 upon expression levels of different surface markers (CD2, CD11a, CD3, CD4, CD8) of human blood T lymphocytes by means of laser flow cytofluorimetry. It is revealed that UV-irradiation at the doses of 151 to 906 J/m2 caused increased expression of CD3, CD4, CD8 membrane markers of the T-lymphocytes. Meanwhile, it was shown that expression levels of CD2 and CD11a adhesion molecules on T-lymphocytes after exposure to UVirradiation (151 to 906 J/m2) remained similar to those for intact cells. UV-irradiation at a dose of 1359 J/ m2 was shown to reduce expression of CD2, CD11a and CD3 markers, along with increased expression level of CD4 and CD8 co-receptor molecules at the T-lymphocytes.V. G. ArtuykhovO. V. PutintsevaS. M. DubovaV. A. BraginaSPb RAACIarticleexpressionadhesion moleculescd3cd4cd8 markersuv-lightImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 4, Pp 361-368 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	expression adhesion molecules cd3 cd4 cd8 markers uv-light Immunologic diseases. Allergy RC581-607
spellingShingle	expression adhesion molecules cd3 cd4 cd8 markers uv-light Immunologic diseases. Allergy RC581-607 V. G. Artuykhov O. V. Putintseva S. M. Dubova V. A. Bragina CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS
description	Abstract. We have studied effects of UV irradiation (240-390 nm) at a dose range of 151 to 1359 J/m2 upon expression levels of different surface markers (CD2, CD11a, CD3, CD4, CD8) of human blood T lymphocytes by means of laser flow cytofluorimetry. It is revealed that UV-irradiation at the doses of 151 to 906 J/m2 caused increased expression of CD3, CD4, CD8 membrane markers of the T-lymphocytes. Meanwhile, it was shown that expression levels of CD2 and CD11a adhesion molecules on T-lymphocytes after exposure to UVirradiation (151 to 906 J/m2) remained similar to those for intact cells. UV-irradiation at a dose of 1359 J/ m2 was shown to reduce expression of CD2, CD11a and CD3 markers, along with increased expression level of CD4 and CD8 co-receptor molecules at the T-lymphocytes.
format	article
author	V. G. Artuykhov O. V. Putintseva S. M. Dubova V. A. Bragina
author_facet	V. G. Artuykhov O. V. Putintseva S. M. Dubova V. A. Bragina
author_sort	V. G. Artuykhov
title	CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS
title_short	CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS
title_full	CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS
title_fullStr	CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS
title_full_unstemmed	CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS
title_sort	changing expression of some molecules on the surface of human blood t-lymphocytes upon uv-irradiation of cell suspensions
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/933f53445f7f4cf785920f55bdae2e26
work_keys_str_mv	AT vgartuykhov changingexpressionofsomemoleculesonthesurfaceofhumanbloodtlymphocytesuponuvirradiationofcellsuspensions AT ovputintseva changingexpressionofsomemoleculesonthesurfaceofhumanbloodtlymphocytesuponuvirradiationofcellsuspensions AT smdubova changingexpressionofsomemoleculesonthesurfaceofhumanbloodtlymphocytesuponuvirradiationofcellsuspensions AT vabragina changingexpressionofsomemoleculesonthesurfaceofhumanbloodtlymphocytesuponuvirradiationofcellsuspensions
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CHANGING EXPRESSION OF SOME MOLECULES ON THE SURFACE OF HUMAN BLOOD T-LYMPHOCYTES UPON UV-IRRADIATION OF CELL SUSPENSIONS

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