Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.

<h4>Aims</h4>The aim of this study was to compare discrepancies between diagnosed and autopsied causes of death in 1,112 hospital autopsies and to determine the factors causing this discrepancies.<h4>Methods</h4>1,112 hospital autopsies between 2010 and 2013 were retrospectiv...

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Autores principales: Stephan D Kurz, Viyan Sido, Hermann Herbst, Bernhard Ulm, Erma Salkic, Thomas M Ruschinski, Claas T Buschmann, Michael Tsokos
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Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/9342a21e4f1045608830c87f4dd38d2d
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spelling oai:doaj.org-article:9342a21e4f1045608830c87f4dd38d2d2021-12-02T20:18:12ZDiscrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.1932-620310.1371/journal.pone.0255490https://doaj.org/article/9342a21e4f1045608830c87f4dd38d2d2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255490https://doaj.org/toc/1932-6203<h4>Aims</h4>The aim of this study was to compare discrepancies between diagnosed and autopsied causes of death in 1,112 hospital autopsies and to determine the factors causing this discrepancies.<h4>Methods</h4>1,112 hospital autopsies between 2010 and 2013 were retrospectively studied. Ante-mortem diagnoses were compared to causes of death as determined by autopsy. Clinical diagnoses were extracted from the autopsy request form, and post-mortem diagnoses were assessed from respective autopsy reports. Variables, such as sex, age, Body Mass Index, category of disease, duration of hospital stay and new-borns were studied in comparison to discrepancy. P-values were derived from the Mann-Whitney U test for the constant features and chi-2 test, p-values < 0,05 were considered significant.<h4>Results</h4>73.9% (n = 822) patients showed no discrepancy between autopsy and clinical diagnosis. The duration of hospitalisation (6 vs. 9 days) and diseases of the cardiovascular system (61.7%) had a significant impact on discrepancies.<h4>Conclusion</h4>Age, cardiovascular diseases and duration of hospital stay significantly affect discrepancies in ante- and post-mortem diagnoses.Stephan D KurzViyan SidoHermann HerbstBernhard UlmErma SalkicThomas M RuschinskiClaas T BuschmannMichael TsokosPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255490 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Stephan D Kurz
Viyan Sido
Hermann Herbst
Bernhard Ulm
Erma Salkic
Thomas M Ruschinski
Claas T Buschmann
Michael Tsokos
Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
description <h4>Aims</h4>The aim of this study was to compare discrepancies between diagnosed and autopsied causes of death in 1,112 hospital autopsies and to determine the factors causing this discrepancies.<h4>Methods</h4>1,112 hospital autopsies between 2010 and 2013 were retrospectively studied. Ante-mortem diagnoses were compared to causes of death as determined by autopsy. Clinical diagnoses were extracted from the autopsy request form, and post-mortem diagnoses were assessed from respective autopsy reports. Variables, such as sex, age, Body Mass Index, category of disease, duration of hospital stay and new-borns were studied in comparison to discrepancy. P-values were derived from the Mann-Whitney U test for the constant features and chi-2 test, p-values < 0,05 were considered significant.<h4>Results</h4>73.9% (n = 822) patients showed no discrepancy between autopsy and clinical diagnosis. The duration of hospitalisation (6 vs. 9 days) and diseases of the cardiovascular system (61.7%) had a significant impact on discrepancies.<h4>Conclusion</h4>Age, cardiovascular diseases and duration of hospital stay significantly affect discrepancies in ante- and post-mortem diagnoses.
format article
author Stephan D Kurz
Viyan Sido
Hermann Herbst
Bernhard Ulm
Erma Salkic
Thomas M Ruschinski
Claas T Buschmann
Michael Tsokos
author_facet Stephan D Kurz
Viyan Sido
Hermann Herbst
Bernhard Ulm
Erma Salkic
Thomas M Ruschinski
Claas T Buschmann
Michael Tsokos
author_sort Stephan D Kurz
title Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
title_short Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
title_full Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
title_fullStr Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
title_full_unstemmed Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
title_sort discrepancies between clinical diagnosis and hospital autopsy: a comparative retrospective analysis of 1,112 cases.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/9342a21e4f1045608830c87f4dd38d2d
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