RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expressed gene pairs.
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Nature Portfolio
2021
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oai:doaj.org-article:934626f2ca0a4f63a03c33541d00ceca2021-12-02T16:56:43ZRN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin10.1038/s41467-021-26083-42041-1723https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26083-4https://doaj.org/toc/2041-1723The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expressed gene pairs.Roberto BandieraRebecca E. WagnerThiago Britto-BorgesChristoph DieterichSabine DietmannSusanne BornelövMichaela FryeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Roberto Bandiera Rebecca E. Wagner Thiago Britto-Borges Christoph Dieterich Sabine Dietmann Susanne Bornelöv Michaela Frye RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin |
description |
The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expressed gene pairs. |
format |
article |
author |
Roberto Bandiera Rebecca E. Wagner Thiago Britto-Borges Christoph Dieterich Sabine Dietmann Susanne Bornelöv Michaela Frye |
author_facet |
Roberto Bandiera Rebecca E. Wagner Thiago Britto-Borges Christoph Dieterich Sabine Dietmann Susanne Bornelöv Michaela Frye |
author_sort |
Roberto Bandiera |
title |
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin |
title_short |
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin |
title_full |
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin |
title_fullStr |
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin |
title_full_unstemmed |
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin |
title_sort |
rn7sk small nuclear rna controls bidirectional transcription of highly expressed gene pairs in skin |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca |
work_keys_str_mv |
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