RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin

The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expressed gene pairs.

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Autores principales: Roberto Bandiera, Rebecca E. Wagner, Thiago Britto-Borges, Christoph Dieterich, Sabine Dietmann, Susanne Bornelöv, Michaela Frye
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca
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spelling oai:doaj.org-article:934626f2ca0a4f63a03c33541d00ceca2021-12-02T16:56:43ZRN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin10.1038/s41467-021-26083-42041-1723https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26083-4https://doaj.org/toc/2041-1723The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expressed gene pairs.Roberto BandieraRebecca E. WagnerThiago Britto-BorgesChristoph DieterichSabine DietmannSusanne BornelövMichaela FryeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Roberto Bandiera
Rebecca E. Wagner
Thiago Britto-Borges
Christoph Dieterich
Sabine Dietmann
Susanne Bornelöv
Michaela Frye
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
description The noncoding RNA RN7SK regulates RNA polymerase II pausing and splicing. Here the authors deplete RN7SK in mouse and human during epidermal stem cell differentiation and reveal a novel role in orchestrating bidirectional transcription of highly expressed gene pairs.
format article
author Roberto Bandiera
Rebecca E. Wagner
Thiago Britto-Borges
Christoph Dieterich
Sabine Dietmann
Susanne Bornelöv
Michaela Frye
author_facet Roberto Bandiera
Rebecca E. Wagner
Thiago Britto-Borges
Christoph Dieterich
Sabine Dietmann
Susanne Bornelöv
Michaela Frye
author_sort Roberto Bandiera
title RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
title_short RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
title_full RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
title_fullStr RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
title_full_unstemmed RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
title_sort rn7sk small nuclear rna controls bidirectional transcription of highly expressed gene pairs in skin
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca
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