Establishment of a Controlled Human Infection Model with a Lyophilized Strain of <named-content content-type="genus-species">Shigella sonnei</named-content> 53G

Establishment of a Controlled Human Infection Model with a Lyophilized Strain of <named-content content-type="genus-species">Shigella sonnei</named-content> 53G

ABSTRACT Controlled human infection models (CHIMs) are useful for vaccine development. To improve on existing models, we developed a CHIM using a lyophilized preparation of Shigella sonnei strain 53G produced using current good manufacturing practice (cGMP). Healthy adults were enrolled in an open-l...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Robert W. Frenck, Michelle Dickey, Akamol E. Suvarnapunya, Lakshmi Chandrasekaran, Robert W. Kaminski, Kristen A. Clarkson, Monica McNeal, Amanda Lynen, Susan Parker, Amy Hoeper, Sachin Mani, Alan Fix, Nicole Maier, Malabi M. Venkatesan, Chad K. Porter
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
controlled human infection models
shigellosis
Shigella
diarrhea
enteric disease
human challenge
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/93466a6d389e45019b54871b82a4c79c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares