Decimated little brown bats show potential for adaptive change

Abstract The degree to which species can rapidly adapt is key to survival in the face of climatic and other anthropogenic changes. For little brown bats (Myotis lucifugus), whose populations have experienced declines of over 90% because of the introduced fungal pathogen that causes white-nose syndro...

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Autores principales:	Giorgia G. Auteri, L. Lacey Knowles
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/934b9f27f4894c98a56c179c410ebe8e
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id	oai:doaj.org-article:934b9f27f4894c98a56c179c410ebe8e
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spelling	oai:doaj.org-article:934b9f27f4894c98a56c179c410ebe8e2021-12-02T14:22:00ZDecimated little brown bats show potential for adaptive change10.1038/s41598-020-59797-42045-2322https://doaj.org/article/934b9f27f4894c98a56c179c410ebe8e2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-59797-4https://doaj.org/toc/2045-2322Abstract The degree to which species can rapidly adapt is key to survival in the face of climatic and other anthropogenic changes. For little brown bats (Myotis lucifugus), whose populations have experienced declines of over 90% because of the introduced fungal pathogen that causes white-nose syndrome (WNS), survival of the species may ultimately depend upon its capacity for adaptive change. Here, we present evidence of selectively driven change (adaptation), despite dramatic nonadaptive genomic shifts (genetic drift) associated with population declines. We compared the genetic makeups of wild survivors versus non-survivors of WNS, and found significant shifts in allele frequencies of genes associated with regulating arousal from hibernation (GABARB1), breakdown of fats (cGMP-PK1), and vocalizations (FOXP2). Changes at these genes are suggestive of evolutionary adaptation, given that WNS causes bats to arouse with unusual frequency from hibernation, contributing to premature depletion of fat reserves. However, whether these putatively adaptive shifts in allele frequencies translate into sufficient increases in survival for the species to rebound in the face of WNS is unknown.Giorgia G. AuteriL. Lacey KnowlesNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Giorgia G. Auteri L. Lacey Knowles Decimated little brown bats show potential for adaptive change
description	Abstract The degree to which species can rapidly adapt is key to survival in the face of climatic and other anthropogenic changes. For little brown bats (Myotis lucifugus), whose populations have experienced declines of over 90% because of the introduced fungal pathogen that causes white-nose syndrome (WNS), survival of the species may ultimately depend upon its capacity for adaptive change. Here, we present evidence of selectively driven change (adaptation), despite dramatic nonadaptive genomic shifts (genetic drift) associated with population declines. We compared the genetic makeups of wild survivors versus non-survivors of WNS, and found significant shifts in allele frequencies of genes associated with regulating arousal from hibernation (GABARB1), breakdown of fats (cGMP-PK1), and vocalizations (FOXP2). Changes at these genes are suggestive of evolutionary adaptation, given that WNS causes bats to arouse with unusual frequency from hibernation, contributing to premature depletion of fat reserves. However, whether these putatively adaptive shifts in allele frequencies translate into sufficient increases in survival for the species to rebound in the face of WNS is unknown.
format	article
author	Giorgia G. Auteri L. Lacey Knowles
author_facet	Giorgia G. Auteri L. Lacey Knowles
author_sort	Giorgia G. Auteri
title	Decimated little brown bats show potential for adaptive change
title_short	Decimated little brown bats show potential for adaptive change
title_full	Decimated little brown bats show potential for adaptive change
title_fullStr	Decimated little brown bats show potential for adaptive change
title_full_unstemmed	Decimated little brown bats show potential for adaptive change
title_sort	decimated little brown bats show potential for adaptive change
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/934b9f27f4894c98a56c179c410ebe8e
work_keys_str_mv	AT giorgiagauteri decimatedlittlebrownbatsshowpotentialforadaptivechange AT llaceyknowles decimatedlittlebrownbatsshowpotentialforadaptivechange
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Decimated little brown bats show potential for adaptive change

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