Development of bifunctional organocatalysts and application to asymmetric total synthesis of naucleofficine I and II
Natural products often contain complex N-fused polycyclic structures with multiple substituents and stereocentres. Here, the authors developed a bifunctional organocatalyst that is instrumental in obtaining such structures and applied it to the total synthesis of naucleofficine I and II in 6 steps.
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Auteurs principaux: | Yong-Hai Yuan, Xue Han, Fu-Ping Zhu, Jin-Miao Tian, Fu-Min Zhang, Xiao-Ming Zhang, Yong-Qiang Tu, Shao-Hua Wang, Xiang Guo |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Sujets: | |
Accès en ligne: | https://doaj.org/article/935061a9dba6497a94cd67bf926fb828 |
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