Development of bifunctional organocatalysts and application to asymmetric total synthesis of naucleofficine I and II

Development of bifunctional organocatalysts and application to asymmetric total synthesis of naucleofficine I and II

Natural products often contain complex N-fused polycyclic structures with multiple substituents and stereocentres. Here, the authors developed a bifunctional organocatalyst that is instrumental in obtaining such structures and applied it to the total synthesis of naucleofficine I and II in 6 steps.

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Detalles Bibliográficos
Autores principales: Yong-Hai Yuan, Xue Han, Fu-Ping Zhu, Jin-Miao Tian, Fu-Min Zhang, Xiao-Ming Zhang, Yong-Qiang Tu, Shao-Hua Wang, Xiang Guo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/935061a9dba6497a94cd67bf926fb828
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