ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.
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Nature Portfolio
2017
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oai:doaj.org-article:9351f20a0619435bbcdc9cfa5fe5baca2021-12-02T17:06:07ZATF3 acts as a rheostat to control JNK signalling during intestinal regeneration10.1038/ncomms142892041-1723https://doaj.org/article/9351f20a0619435bbcdc9cfa5fe5baca2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14289https://doaj.org/toc/2041-1723Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.Jun ZhouBruce A. EdgarMichael BoutrosNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
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Science Q Jun Zhou Bruce A. Edgar Michael Boutros ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration |
description |
Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection. |
format |
article |
author |
Jun Zhou Bruce A. Edgar Michael Boutros |
author_facet |
Jun Zhou Bruce A. Edgar Michael Boutros |
author_sort |
Jun Zhou |
title |
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration |
title_short |
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration |
title_full |
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration |
title_fullStr |
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration |
title_full_unstemmed |
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration |
title_sort |
atf3 acts as a rheostat to control jnk signalling during intestinal regeneration |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/9351f20a0619435bbcdc9cfa5fe5baca |
work_keys_str_mv |
AT junzhou atf3actsasarheostattocontroljnksignallingduringintestinalregeneration AT bruceaedgar atf3actsasarheostattocontroljnksignallingduringintestinalregeneration AT michaelboutros atf3actsasarheostattocontroljnksignallingduringintestinalregeneration |
_version_ |
1718381742637711360 |