ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration

Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.

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Autores principales: Jun Zhou, Bruce A. Edgar, Michael Boutros
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9351f20a0619435bbcdc9cfa5fe5baca
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spelling oai:doaj.org-article:9351f20a0619435bbcdc9cfa5fe5baca2021-12-02T17:06:07ZATF3 acts as a rheostat to control JNK signalling during intestinal regeneration10.1038/ncomms142892041-1723https://doaj.org/article/9351f20a0619435bbcdc9cfa5fe5baca2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14289https://doaj.org/toc/2041-1723Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.Jun ZhouBruce A. EdgarMichael BoutrosNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jun Zhou
Bruce A. Edgar
Michael Boutros
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
description Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.
format article
author Jun Zhou
Bruce A. Edgar
Michael Boutros
author_facet Jun Zhou
Bruce A. Edgar
Michael Boutros
author_sort Jun Zhou
title ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
title_short ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
title_full ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
title_fullStr ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
title_full_unstemmed ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
title_sort atf3 acts as a rheostat to control jnk signalling during intestinal regeneration
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/9351f20a0619435bbcdc9cfa5fe5baca
work_keys_str_mv AT junzhou atf3actsasarheostattocontroljnksignallingduringintestinalregeneration
AT bruceaedgar atf3actsasarheostattocontroljnksignallingduringintestinalregeneration
AT michaelboutros atf3actsasarheostattocontroljnksignallingduringintestinalregeneration
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