Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia

Shenglin She,1,* Bei Zhang,1,* Lin Mi,1 Haijing Li,1 Qijie Kuang,1 Taiyong Bi,2 Yingjun Zheng1 1Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), National Clinical Research Center on Mental Disorders (Changsha), Guangzhou 510370, Chin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	She S, Zhang B, Mi L, Li H, Kuang Q, Bi T, Zheng Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Visual working memory First-episode schizophrenia Face perception Match-to-sample Memory load Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/93567c0190da4cbcae76d2ad8fa958c5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:93567c0190da4cbcae76d2ad8fa958c5
record_format	dspace
spelling	oai:doaj.org-article:93567c0190da4cbcae76d2ad8fa958c52021-12-02T05:06:42ZStimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia1178-2021https://doaj.org/article/93567c0190da4cbcae76d2ad8fa958c52019-02-01T00:00:00Zhttps://www.dovepress.com/stimuli-may-have-little-impact-on-the-deficit-of-visual-working-memory-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Shenglin She,1,* Bei Zhang,1,* Lin Mi,1 Haijing Li,1 Qijie Kuang,1 Taiyong Bi,2 Yingjun Zheng1 1Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), National Clinical Research Center on Mental Disorders (Changsha), Guangzhou 510370, China; 2School of Management, Zunyi Medical University, Guizhou 563000, China *These authors contributed equally to this work Purpose: Working memory (WM) deficits have been observed in people with schizophrenia (SZ) and are considered a core cognitive dysfunction in these patients. However, little is known about how stimuli and memory load influence visual WM deficits. Patients and methods: In the present study, we adopted a match-to-sample task to examine the visual WM in 18 first-episode patients with SZ and 18 healthy controls (HCs). Faces and houses were used as the stimuli, and there were two levels of memory load – one item and two items; the average accuracy (ACC) and reaction time were calculated for each condition. The Positive and Negative Syndrome Scale and the Personal and Social Performance scale were used to assess the psychiatric symptoms and social function, respectively. Results: The results showed equivalent levels of WM deficit when using face and house stimuli. Moreover, the WM deficits were not related to the duration of illness, medication, or SZ symptoms. Conclusion: These results demonstrate that stimuli may have little impact on ACC in WM tasks in people with SZ. In addition, the memory load may have little impact on WM ACC when the load is relatively low. Keywords: visual working memory, first-episode schizophrenia, face perception, match-to-sample, memory load, working memory deficitShe SZhang BMi LLi HKuang QBi TZheng YDove Medical PressarticleVisual working memoryFirst-episode schizophreniaFace perceptionMatch-to-sampleMemory loadNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 15, Pp 481-489 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Visual working memory First-episode schizophrenia Face perception Match-to-sample Memory load Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Visual working memory First-episode schizophrenia Face perception Match-to-sample Memory load Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 She S Zhang B Mi L Li H Kuang Q Bi T Zheng Y Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
description	Shenglin She,1,* Bei Zhang,1,* Lin Mi,1 Haijing Li,1 Qijie Kuang,1 Taiyong Bi,2 Yingjun Zheng1 1Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), National Clinical Research Center on Mental Disorders (Changsha), Guangzhou 510370, China; 2School of Management, Zunyi Medical University, Guizhou 563000, China *These authors contributed equally to this work Purpose: Working memory (WM) deficits have been observed in people with schizophrenia (SZ) and are considered a core cognitive dysfunction in these patients. However, little is known about how stimuli and memory load influence visual WM deficits. Patients and methods: In the present study, we adopted a match-to-sample task to examine the visual WM in 18 first-episode patients with SZ and 18 healthy controls (HCs). Faces and houses were used as the stimuli, and there were two levels of memory load – one item and two items; the average accuracy (ACC) and reaction time were calculated for each condition. The Positive and Negative Syndrome Scale and the Personal and Social Performance scale were used to assess the psychiatric symptoms and social function, respectively. Results: The results showed equivalent levels of WM deficit when using face and house stimuli. Moreover, the WM deficits were not related to the duration of illness, medication, or SZ symptoms. Conclusion: These results demonstrate that stimuli may have little impact on ACC in WM tasks in people with SZ. In addition, the memory load may have little impact on WM ACC when the load is relatively low. Keywords: visual working memory, first-episode schizophrenia, face perception, match-to-sample, memory load, working memory deficit
format	article
author	She S Zhang B Mi L Li H Kuang Q Bi T Zheng Y
author_facet	She S Zhang B Mi L Li H Kuang Q Bi T Zheng Y
author_sort	She S
title	Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
title_short	Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
title_full	Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
title_fullStr	Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
title_full_unstemmed	Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
title_sort	stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/93567c0190da4cbcae76d2ad8fa958c5
work_keys_str_mv	AT shes stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia AT zhangb stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia AT mil stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia AT lih stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia AT kuangq stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia AT bit stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia AT zhengy stimulimayhavelittleimpactonthedeficitofvisualworkingmemoryaccuracyinfirstepisodeschizophrenia
_version_	1718400606793629696

Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia

Ejemplares similares