An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer

An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer

Expression patterns of immune checkpoints in patients with gastric cancer remain poorly characterized. Here the authors propose an immune scoring system based on the expression of six immunosuppressive ligands to improve the prognostic accuracy in gastric cancer patients and drive the selection of c...

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Autores principales: Jia-Bin Wang, Ping Li, Xiao-Long Liu, Qiao-Ling Zheng, Yu-Bin Ma, Ya-Jun Zhao, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Li-Chao Liu, Ning-Zi Lian, Ying-Hong Yang, Chang-Ming Huang, Chao-Hui Zheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/935dcdd3fb754d679c625e6ae83c17b9
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spelling oai:doaj.org-article:935dcdd3fb754d679c625e6ae83c17b92021-12-02T14:16:55ZAn immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer10.1038/s41467-020-20260-72041-1723https://doaj.org/article/935dcdd3fb754d679c625e6ae83c17b92020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20260-7https://doaj.org/toc/2041-1723Expression patterns of immune checkpoints in patients with gastric cancer remain poorly characterized. Here the authors propose an immune scoring system based on the expression of six immunosuppressive ligands to improve the prognostic accuracy in gastric cancer patients and drive the selection of candidates for adjuvant chemotherapy.Jia-Bin WangPing LiXiao-Long LiuQiao-Ling ZhengYu-Bin MaYa-Jun ZhaoJian-Wei XieJian-Xian LinJun LuQi-Yue ChenLong-Long CaoMi LinLi-Chao LiuNing-Zi LianYing-Hong YangChang-Ming HuangChao-Hui ZhengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jia-Bin Wang
Ping Li
Xiao-Long Liu
Qiao-Ling Zheng
Yu-Bin Ma
Ya-Jun Zhao
Jian-Wei Xie
Jian-Xian Lin
Jun Lu
Qi-Yue Chen
Long-Long Cao
Mi Lin
Li-Chao Liu
Ning-Zi Lian
Ying-Hong Yang
Chang-Ming Huang
Chao-Hui Zheng
An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
description Expression patterns of immune checkpoints in patients with gastric cancer remain poorly characterized. Here the authors propose an immune scoring system based on the expression of six immunosuppressive ligands to improve the prognostic accuracy in gastric cancer patients and drive the selection of candidates for adjuvant chemotherapy.
format article
author Jia-Bin Wang
Ping Li
Xiao-Long Liu
Qiao-Ling Zheng
Yu-Bin Ma
Ya-Jun Zhao
Jian-Wei Xie
Jian-Xian Lin
Jun Lu
Qi-Yue Chen
Long-Long Cao
Mi Lin
Li-Chao Liu
Ning-Zi Lian
Ying-Hong Yang
Chang-Ming Huang
Chao-Hui Zheng
author_facet Jia-Bin Wang
Ping Li
Xiao-Long Liu
Qiao-Ling Zheng
Yu-Bin Ma
Ya-Jun Zhao
Jian-Wei Xie
Jian-Xian Lin
Jun Lu
Qi-Yue Chen
Long-Long Cao
Mi Lin
Li-Chao Liu
Ning-Zi Lian
Ying-Hong Yang
Chang-Ming Huang
Chao-Hui Zheng
author_sort Jia-Bin Wang
title An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
title_short An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
title_full An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
title_fullStr An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
title_full_unstemmed An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
title_sort immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/935dcdd3fb754d679c625e6ae83c17b9
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