Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure

Jacky WY Lee,1 Jimmy SM Lai,1 Doris WF Yick,2 Can YF Yuen21Department of Ophthalmology, University of Hong Kong, 2Department of Ophthalmology, The Caritas Medical Centre, Kowloon West Cluster, Hong Kong, People&rsquo;s Republic of ChinaBackground: The purpose of this study was to compare the...

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Autores principales:	Lee JW, Lai JS, Yick DW, Yuen CY
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9365ae6e1fae44d495d3a19700d385a9
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spelling	oai:doaj.org-article:9365ae6e1fae44d495d3a19700d385a92021-12-02T07:49:31ZArgon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure1177-54671177-5483https://doaj.org/article/9365ae6e1fae44d495d3a19700d385a92013-01-01T00:00:00Zhttp://www.dovepress.com/argon-laser-peripheral-iridoplasty-versus-systemic-intraocular-pressur-a11896https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Jacky WY Lee,1 Jimmy SM Lai,1 Doris WF Yick,2 Can YF Yuen21Department of Ophthalmology, University of Hong Kong, 2Department of Ophthalmology, The Caritas Medical Centre, Kowloon West Cluster, Hong Kong, People&rsquo;s Republic of ChinaBackground: The purpose of this study was to compare the efficacy and safety of argon laser peripheral iridoplasty (ALPI) and systemic intraocular pressure (IOP)-lowering medications in the immediate management of acute phacomorphic angle closure.Methods: Consecutive cases of acute phacomorphic angle closure were randomized to receive ALPI and an intravenous or oral carbonic anhydrase inhibitor as initial treatment. Intravenous mannitol was administered for presenting IOP &gt; 60 mmHg or IOP &gt; 40 mmHg 2 hours posttreatment in both arms.Results: Of 10 consecutive cases, six received medical therapy and four received ALPI. Fifty percent in the medical group and none in the ALPI group required intravenous mannitol. The ALPI group took less time to achieve IOP &lt; 25 mmHg (18.8 &plusmn; 7.5 minutes versus 115.0 &plusmn; 97.0 minutes, P = 0.001, F test); had a greater IOP reduction within 30 minutes (69.8% &plusmn; 7.7% versus 40.9 &plusmn; 23.9%, P = 0.03, t-test); and had a consistently smaller post-attack cup to disc ratio (0.50 &plusmn; 0.02 versus 0.60 &plusmn; 0.20, P = 0.002, F test).Conclusion: ALPI offers greater safety, consistency, and efficacy than systemic IOP-lowering medications as initial treatment for phacomorphic angle closure.Keywords: phacomorphic, glaucoma, argon laser peripheral iridoplasty, medical, intraocular pressureLee JWLai JSYick DWYuen CYDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 63-69 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Lee JW Lai JS Yick DW Yuen CY Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
description	Jacky WY Lee,1 Jimmy SM Lai,1 Doris WF Yick,2 Can YF Yuen21Department of Ophthalmology, University of Hong Kong, 2Department of Ophthalmology, The Caritas Medical Centre, Kowloon West Cluster, Hong Kong, People&rsquo;s Republic of ChinaBackground: The purpose of this study was to compare the efficacy and safety of argon laser peripheral iridoplasty (ALPI) and systemic intraocular pressure (IOP)-lowering medications in the immediate management of acute phacomorphic angle closure.Methods: Consecutive cases of acute phacomorphic angle closure were randomized to receive ALPI and an intravenous or oral carbonic anhydrase inhibitor as initial treatment. Intravenous mannitol was administered for presenting IOP &gt; 60 mmHg or IOP &gt; 40 mmHg 2 hours posttreatment in both arms.Results: Of 10 consecutive cases, six received medical therapy and four received ALPI. Fifty percent in the medical group and none in the ALPI group required intravenous mannitol. The ALPI group took less time to achieve IOP &lt; 25 mmHg (18.8 &plusmn; 7.5 minutes versus 115.0 &plusmn; 97.0 minutes, P = 0.001, F test); had a greater IOP reduction within 30 minutes (69.8% &plusmn; 7.7% versus 40.9 &plusmn; 23.9%, P = 0.03, t-test); and had a consistently smaller post-attack cup to disc ratio (0.50 &plusmn; 0.02 versus 0.60 &plusmn; 0.20, P = 0.002, F test).Conclusion: ALPI offers greater safety, consistency, and efficacy than systemic IOP-lowering medications as initial treatment for phacomorphic angle closure.Keywords: phacomorphic, glaucoma, argon laser peripheral iridoplasty, medical, intraocular pressure
format	article
author	Lee JW Lai JS Yick DW Yuen CY
author_facet	Lee JW Lai JS Yick DW Yuen CY
author_sort	Lee JW
title	Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
title_short	Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
title_full	Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
title_fullStr	Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
title_full_unstemmed	Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
title_sort	argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/9365ae6e1fae44d495d3a19700d385a9
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Argon laser peripheral iridoplasty versus systemic intraocular pressure-lowering medications as immediate management for acute phacomorphic angle closure

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