Indirect DNA readout by an H-NS related protein: structure of the DNA complex of the C-terminal domain of Ler.

Ler, a member of the H-NS protein family, is the master regulator of the LEE pathogenicity island in virulent Escherichia coli strains. Here, we determined the structure of a complex between the DNA-binding domain of Ler (CT-Ler) and a 15-mer DNA duplex. CT-Ler recognizes a preexisting structural pa...

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Autores principales: Tiago N Cordeiro, Holger Schmidt, Cristina Madrid, Antonio Juárez, Pau Bernadó, Christian Griesinger, Jesús García, Miquel Pons
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/9365c281407946809a074e0fe918ae66
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