BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning

The regulatory networks that govern chromatin accessibility and gene expression in brown and beigeadipocytes remain to be fully elucidated. Here the authors use fat-specific inactivation of BAF60a toreveal a differential role for this chromatin remodeling factor in brown fat thermogenesis and coldin...

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Autores principales:	Tongyu Liu, Lin Mi, Jing Xiong, Peter Orchard, Qi Yu, Lei Yu, Xu-Yun Zhao, Zhuo-Xian Meng, Stephen C. J. Parker, Jiandie D. Lin, Siming Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9367a3385a00407688e6ae5ad541e1f3
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spelling	oai:doaj.org-article:9367a3385a00407688e6ae5ad541e1f32021-12-02T16:50:26ZBAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning10.1038/s41467-020-16148-12041-1723https://doaj.org/article/9367a3385a00407688e6ae5ad541e1f32020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16148-1https://doaj.org/toc/2041-1723The regulatory networks that govern chromatin accessibility and gene expression in brown and beigeadipocytes remain to be fully elucidated. Here the authors use fat-specific inactivation of BAF60a toreveal a differential role for this chromatin remodeling factor in brown fat thermogenesis and coldinduced browning of inguinal fat.Tongyu LiuLin MiJing XiongPeter OrchardQi YuLei YuXu-Yun ZhaoZhuo-Xian MengStephen C. J. ParkerJiandie D. LinSiming LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tongyu Liu Lin Mi Jing Xiong Peter Orchard Qi Yu Lei Yu Xu-Yun Zhao Zhuo-Xian Meng Stephen C. J. Parker Jiandie D. Lin Siming Li BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
description	The regulatory networks that govern chromatin accessibility and gene expression in brown and beigeadipocytes remain to be fully elucidated. Here the authors use fat-specific inactivation of BAF60a toreveal a differential role for this chromatin remodeling factor in brown fat thermogenesis and coldinduced browning of inguinal fat.
format	article
author	Tongyu Liu Lin Mi Jing Xiong Peter Orchard Qi Yu Lei Yu Xu-Yun Zhao Zhuo-Xian Meng Stephen C. J. Parker Jiandie D. Lin Siming Li
author_facet	Tongyu Liu Lin Mi Jing Xiong Peter Orchard Qi Yu Lei Yu Xu-Yun Zhao Zhuo-Xian Meng Stephen C. J. Parker Jiandie D. Lin Siming Li
author_sort	Tongyu Liu
title	BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
title_short	BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
title_full	BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
title_fullStr	BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
title_full_unstemmed	BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
title_sort	baf60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/9367a3385a00407688e6ae5ad541e1f3
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BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning

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