Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen

Naonori Masuda, Masashi Kojima, Mariko Yamashita, Tomo Nishi, Nahoko Ogata Department of Ophthalmology, Nara Medical University, Nara, Japan Purpose: To compare the choroidal structure beneath the macular area in eyes with reticular pseudodrusen (RPD) and age-matched controls.Methods: This study w...

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Autores principales:	Masuda N, Kojima M, Yamashita M, Nishi T, Ogata N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	reticular pesudodrusen age-related macular degeneration choroidal structure binarization method Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/936814e5725a45c5b65daf91fe10ee90
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spelling	oai:doaj.org-article:936814e5725a45c5b65daf91fe10ee902021-12-02T09:07:47ZChoroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen1177-5483https://doaj.org/article/936814e5725a45c5b65daf91fe10ee902017-04-01T00:00:00Zhttps://www.dovepress.com/choroidal-structure-determined-by-binarizing-optical-coherence-tomogra-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Naonori Masuda, Masashi Kojima, Mariko Yamashita, Tomo Nishi, Nahoko Ogata Department of Ophthalmology, Nara Medical University, Nara, Japan Purpose: To compare the choroidal structure beneath the macular area in eyes with reticular pseudodrusen (RPD) and age-matched controls.Methods: This study was performed at Nara Medical University Hospital, Japan. Twenty eyes of 14 patients (82.3±4.2 years, mean ± standard deviation) with RPD and 35 eyes of 20 age-matched controls (81.5±6.0 years) were studied. The choroidal structure was determined by binarizing the images obtained by enhanced depth imaging optical coherence tomography in all patients and controls. The total, luminal, and stromal choroidal areas were quantified by the binarization method.Results: The total choroidal area of the eyes with RPD was significantly smaller than that of control eyes (P=0.001, unpaired t-test). Both the luminal and stromal areas in eyes with RPD were significantly smaller than that of control eyes (P=0.001, paired t-test), but there was no significant difference in the luminal/stromal ratio between eyes with RPD and control eyes.Conclusion: The total, luminal, and stromal choroidal areas in eyes with RPD were smaller than those of the control eyes. The reduction of the choroidal luminal and stromal areas may be due to a loss of the oxygen demand of the choroid due to RPE dysfunction. Keywords: reticular pseudodrusen, age-related macular degeneration, choroidal structure, binarization methodMasuda NKojima MYamashita MNishi TOgata NDove Medical Pressarticlereticular pesudodrusenage-related macular degenerationchoroidal structurebinarization methodOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 791-795 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	reticular pesudodrusen age-related macular degeneration choroidal structure binarization method Ophthalmology RE1-994
spellingShingle	reticular pesudodrusen age-related macular degeneration choroidal structure binarization method Ophthalmology RE1-994 Masuda N Kojima M Yamashita M Nishi T Ogata N Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
description	Naonori Masuda, Masashi Kojima, Mariko Yamashita, Tomo Nishi, Nahoko Ogata Department of Ophthalmology, Nara Medical University, Nara, Japan Purpose: To compare the choroidal structure beneath the macular area in eyes with reticular pseudodrusen (RPD) and age-matched controls.Methods: This study was performed at Nara Medical University Hospital, Japan. Twenty eyes of 14 patients (82.3±4.2 years, mean ± standard deviation) with RPD and 35 eyes of 20 age-matched controls (81.5±6.0 years) were studied. The choroidal structure was determined by binarizing the images obtained by enhanced depth imaging optical coherence tomography in all patients and controls. The total, luminal, and stromal choroidal areas were quantified by the binarization method.Results: The total choroidal area of the eyes with RPD was significantly smaller than that of control eyes (P=0.001, unpaired t-test). Both the luminal and stromal areas in eyes with RPD were significantly smaller than that of control eyes (P=0.001, paired t-test), but there was no significant difference in the luminal/stromal ratio between eyes with RPD and control eyes.Conclusion: The total, luminal, and stromal choroidal areas in eyes with RPD were smaller than those of the control eyes. The reduction of the choroidal luminal and stromal areas may be due to a loss of the oxygen demand of the choroid due to RPE dysfunction. Keywords: reticular pseudodrusen, age-related macular degeneration, choroidal structure, binarization method
format	article
author	Masuda N Kojima M Yamashita M Nishi T Ogata N
author_facet	Masuda N Kojima M Yamashita M Nishi T Ogata N
author_sort	Masuda N
title	Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
title_short	Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
title_full	Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
title_fullStr	Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
title_full_unstemmed	Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
title_sort	choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/936814e5725a45c5b65daf91fe10ee90
work_keys_str_mv	AT masudan choroidalstructuredeterminedbybinarizingopticalcoherencetomographyimagesineyeswithreticularpseudodrusen AT kojimam choroidalstructuredeterminedbybinarizingopticalcoherencetomographyimagesineyeswithreticularpseudodrusen AT yamashitam choroidalstructuredeterminedbybinarizingopticalcoherencetomographyimagesineyeswithreticularpseudodrusen AT nishit choroidalstructuredeterminedbybinarizingopticalcoherencetomographyimagesineyeswithreticularpseudodrusen AT ogatan choroidalstructuredeterminedbybinarizingopticalcoherencetomographyimagesineyeswithreticularpseudodrusen
_version_	1718398258171084800

Choroidal structure determined by binarizing optical coherence tomography images in eyes with reticular pseudodrusen

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