Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila

The emergence of the adult fruit flies from the pupae is jointly regulated by the central and peripheral clocks. Selchoet al. show that synchronization of the two clocks is mediated by the master clock brain neurons producing sNPF, and non-clock PTTH neurons that regulate the peripheral clock produc...

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Autores principales:	Mareike Selcho, Carola Millán, Angelina Palacios-Muñoz, Franziska Ruf, Lilian Ubillo, Jiangtian Chen, Gregor Bergmann, Chihiro Ito, Valeria Silva, Christian Wegener, John Ewer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/93748c81ccfb4e92857d11a399451f8e
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spelling	oai:doaj.org-article:93748c81ccfb4e92857d11a399451f8e2021-12-02T17:01:17ZCentral and peripheral clocks are coupled by a neuropeptide pathway in Drosophila10.1038/ncomms155632041-1723https://doaj.org/article/93748c81ccfb4e92857d11a399451f8e2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15563https://doaj.org/toc/2041-1723The emergence of the adult fruit flies from the pupae is jointly regulated by the central and peripheral clocks. Selchoet al. show that synchronization of the two clocks is mediated by the master clock brain neurons producing sNPF, and non-clock PTTH neurons that regulate the peripheral clock producing the steroid moulting hormone, ecdysone.Mareike SelchoCarola MillánAngelina Palacios-MuñozFranziska RufLilian UbilloJiangtian ChenGregor BergmannChihiro ItoValeria SilvaChristian WegenerJohn EwerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mareike Selcho Carola Millán Angelina Palacios-Muñoz Franziska Ruf Lilian Ubillo Jiangtian Chen Gregor Bergmann Chihiro Ito Valeria Silva Christian Wegener John Ewer Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila
description	The emergence of the adult fruit flies from the pupae is jointly regulated by the central and peripheral clocks. Selchoet al. show that synchronization of the two clocks is mediated by the master clock brain neurons producing sNPF, and non-clock PTTH neurons that regulate the peripheral clock producing the steroid moulting hormone, ecdysone.
format	article
author	Mareike Selcho Carola Millán Angelina Palacios-Muñoz Franziska Ruf Lilian Ubillo Jiangtian Chen Gregor Bergmann Chihiro Ito Valeria Silva Christian Wegener John Ewer
author_facet	Mareike Selcho Carola Millán Angelina Palacios-Muñoz Franziska Ruf Lilian Ubillo Jiangtian Chen Gregor Bergmann Chihiro Ito Valeria Silva Christian Wegener John Ewer
author_sort	Mareike Selcho
title	Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila
title_short	Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila
title_full	Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila
title_fullStr	Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila
title_full_unstemmed	Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila
title_sort	central and peripheral clocks are coupled by a neuropeptide pathway in drosophila
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/93748c81ccfb4e92857d11a399451f8e
work_keys_str_mv	AT mareikeselcho centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT carolamillan centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT angelinapalaciosmunoz centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT franziskaruf centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT lilianubillo centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT jiangtianchen centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT gregorbergmann centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT chihiroito centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT valeriasilva centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT christianwegener centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila AT johnewer centralandperipheralclocksarecoupledbyaneuropeptidepathwayindrosophila
_version_	1718382224143810560

Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila

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