Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide

Abstract Septic acute kidney injury (AKI) and myocardial dysfunction are leading causes of mortality with no accepted method of therapy. In this study we demonstrate the role of growth differentiating factor 15 (GDF15) in septic AKI and myocardial dysfunction using a murine lipopolysaccharide (LPS)-...

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Auteurs principaux: Palida Abulizi, Neruja Loganathan, Duo Zhao, Tina Mele, Yixin Zhang, Terry Zwiep, Kexiang Liu, Xiufen Zheng
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/937a31d3299f4a209726346449af42c7
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