Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.

Shoulder rotator cuff tendinopathy is a common debilitating condition that affects a person daily function and the quality of life. Despite its frequent occurrence, the best treatment is still inconclusive. This review assessed the clinical effect of platelet-rich plasma injection for rotator cuff t...

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Autores principales:	Mohamad Shariff A Hamid, Shariff Ghazali Sazlina
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/937cdf13499c4437ad3de59de2853d6e
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spelling	oai:doaj.org-article:937cdf13499c4437ad3de59de2853d6e2021-12-02T20:11:24ZPlatelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.1932-620310.1371/journal.pone.0251111https://doaj.org/article/937cdf13499c4437ad3de59de2853d6e2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251111https://doaj.org/toc/1932-6203Shoulder rotator cuff tendinopathy is a common debilitating condition that affects a person daily function and the quality of life. Despite its frequent occurrence, the best treatment is still inconclusive. This review assessed the clinical effect of platelet-rich plasma injection for rotator cuff tendinopathy. A systematic literature search was conducted using CINAHL, Medline, SCOPUS, SPORTSDiscus and Web of Science databases to retrieve articles published in peer-reviewed journals until December 2020. Randomised controlled trials (RCTs), which compared clinical effects of PRP injection to the usual care among adults diagnosed with rotator cuff conditions were reviewed. The main outcomes of interest were changes in shoulder pain symptoms and shoulder functions. All variables were analysed using random effects meta-analyses. Eight RCTs were reviewed in this study. The risk of bias for randomization was low for 6 RCTs, one study had unclear risk and the other was a high risk. Studies vary on the PRP techniques including preparation and injections. Moreover, the control intervention also differs. Four studies compared PRP with normal saline injection while in the remaining 4 RCTs the control intervention were rehabilitation program and dry needling. Meta-analysis of selected studies showed that PRP injection was safe and effective intervention for long-term pain control and shoulder function in patients with RC disorders.Mohamad Shariff A HamidShariff Ghazali SazlinaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 5, p e0251111 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mohamad Shariff A Hamid Shariff Ghazali Sazlina Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.
description	Shoulder rotator cuff tendinopathy is a common debilitating condition that affects a person daily function and the quality of life. Despite its frequent occurrence, the best treatment is still inconclusive. This review assessed the clinical effect of platelet-rich plasma injection for rotator cuff tendinopathy. A systematic literature search was conducted using CINAHL, Medline, SCOPUS, SPORTSDiscus and Web of Science databases to retrieve articles published in peer-reviewed journals until December 2020. Randomised controlled trials (RCTs), which compared clinical effects of PRP injection to the usual care among adults diagnosed with rotator cuff conditions were reviewed. The main outcomes of interest were changes in shoulder pain symptoms and shoulder functions. All variables were analysed using random effects meta-analyses. Eight RCTs were reviewed in this study. The risk of bias for randomization was low for 6 RCTs, one study had unclear risk and the other was a high risk. Studies vary on the PRP techniques including preparation and injections. Moreover, the control intervention also differs. Four studies compared PRP with normal saline injection while in the remaining 4 RCTs the control intervention were rehabilitation program and dry needling. Meta-analysis of selected studies showed that PRP injection was safe and effective intervention for long-term pain control and shoulder function in patients with RC disorders.
format	article
author	Mohamad Shariff A Hamid Shariff Ghazali Sazlina
author_facet	Mohamad Shariff A Hamid Shariff Ghazali Sazlina
author_sort	Mohamad Shariff A Hamid
title	Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.
title_short	Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.
title_full	Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.
title_fullStr	Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.
title_full_unstemmed	Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.
title_sort	platelet-rich plasma for rotator cuff tendinopathy: a systematic review and meta-analysis.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/937cdf13499c4437ad3de59de2853d6e
work_keys_str_mv	AT mohamadshariffahamid plateletrichplasmaforrotatorcufftendinopathyasystematicreviewandmetaanalysis AT shariffghazalisazlina plateletrichplasmaforrotatorcufftendinopathyasystematicreviewandmetaanalysis
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Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.

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