Gene Essentiality Analyzed by <italic toggle="yes">In Vivo</italic> Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of <italic toggle="yes">Candida albicans</italic>

Gene Essentiality Analyzed by <italic toggle="yes">In Vivo</italic> Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of <italic toggle="yes">Candida albicans</italic>

ABSTRACT Knowing the full set of essential genes for a given organism provides important information about ways to promote, and to limit, its growth and survival. For many non-model organisms, the lack of a stable haploid state and low transformation efficiencies impede the use of conventional appro...

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Bibliographic Details
Main Authors: Ella Shtifman Segal, Vladimir Gritsenko, Anton Levitan, Bhawna Yadav, Naama Dror, Jacob L. Steenwyk, Yael Silberberg, Kevin Mielich, Antonis Rokas, Neil A. R. Gow, Reinhard Kunze, Roded Sharan, Judith Berman
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Candida albicans
genome analysis
genomics
machine learning
phenotypic identification
transposons
Microbiology
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Online Access:https://doaj.org/article/93849fe3376347c2b111ba66ca743a9a
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