Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM.

The NS1 protein from avian influenza A viruses contains a PDZ binding motif (PBM) at its carboxyl terminus with the consensus sequence ESEV. The ESEV PBM confers binding to several cellular PDZ proteins, including Dlg1, MAGI-1 and Scribble. The interaction between NS1 and Scribble protects infected...

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Autores principales: Manish Kumar, Hongbing Liu, Andrew P Rice
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/9387cd57eb6d4a76a6d6884f504fbcd6
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