Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights

Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights

Understanding the molecular and phenotypic profile of colorectal cancer (CRC) in West Africa is important for early detection and treatment. Here, the authors use a multigene next-generation sequencing panel to identify genomic differences in Nigerian CRCs compared to those from TCGA and MSKCC cohor...

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Autores principales: Olusegun Isaac Alatise, Gregory C. Knapp, Avinash Sharma, Walid K. Chatila, Olukayode A. Arowolo, Olalekan Olasehinde, Olusola C. Famurewa, Adeleye D. Omisore, Akinwumi O. Komolafe, Olaejinrinde O. Olaofe, Aba I. Katung, David E. Ibikunle, Adedeji A. Egberongbe, Samuel A. Olatoke, Sulaiman O. Agodirin, Olusola A. Adesiyun, Ademola Adeyeye, Oladapo A. Kolawole, Akinwumi O. Olakanmi, Kanika Arora, Jeremy Constable, Ronak Shah, Azfar Basunia, Brooke Sylvester, Chao Wu, Martin R. Weiser, Ken Seier, Mithat Gonen, Zsofia K. Stadler, Yelena Kemel, Efsevia Vakiani, Michael F. Berger, Timothy A. Chan, David B. Solit, Jinru Shia, Francisco Sanchez-Vega, Nikolaus Schultz, Murray Brennan, J. Joshua Smith, T. Peter Kingham
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:939275ce40494796b17543b64bb2bcce2021-11-28T12:33:54ZMolecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights10.1038/s41467-021-27106-w2041-1723https://doaj.org/article/939275ce40494796b17543b64bb2bcce2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27106-whttps://doaj.org/toc/2041-1723Understanding the molecular and phenotypic profile of colorectal cancer (CRC) in West Africa is important for early detection and treatment. Here, the authors use a multigene next-generation sequencing panel to identify genomic differences in Nigerian CRCs compared to those from TCGA and MSKCC cohorts.Olusegun Isaac AlatiseGregory C. KnappAvinash SharmaWalid K. ChatilaOlukayode A. ArowoloOlalekan OlasehindeOlusola C. FamurewaAdeleye D. OmisoreAkinwumi O. KomolafeOlaejinrinde O. OlaofeAba I. KatungDavid E. IbikunleAdedeji A. EgberongbeSamuel A. OlatokeSulaiman O. AgodirinOlusola A. AdesiyunAdemola AdeyeyeOladapo A. KolawoleAkinwumi O. OlakanmiKanika AroraJeremy ConstableRonak ShahAzfar BasuniaBrooke SylvesterChao WuMartin R. WeiserKen SeierMithat GonenZsofia K. StadlerYelena KemelEfsevia VakianiMichael F. BergerTimothy A. ChanDavid B. SolitJinru ShiaFrancisco Sanchez-VegaNikolaus SchultzMurray BrennanJ. Joshua SmithT. Peter KinghamNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Olusegun Isaac Alatise
Gregory C. Knapp
Avinash Sharma
Walid K. Chatila
Olukayode A. Arowolo
Olalekan Olasehinde
Olusola C. Famurewa
Adeleye D. Omisore
Akinwumi O. Komolafe
Olaejinrinde O. Olaofe
Aba I. Katung
David E. Ibikunle
Adedeji A. Egberongbe
Samuel A. Olatoke
Sulaiman O. Agodirin
Olusola A. Adesiyun
Ademola Adeyeye
Oladapo A. Kolawole
Akinwumi O. Olakanmi
Kanika Arora
Jeremy Constable
Ronak Shah
Azfar Basunia
Brooke Sylvester
Chao Wu
Martin R. Weiser
Ken Seier
Mithat Gonen
Zsofia K. Stadler
Yelena Kemel
Efsevia Vakiani
Michael F. Berger
Timothy A. Chan
David B. Solit
Jinru Shia
Francisco Sanchez-Vega
Nikolaus Schultz
Murray Brennan
J. Joshua Smith
T. Peter Kingham
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
description Understanding the molecular and phenotypic profile of colorectal cancer (CRC) in West Africa is important for early detection and treatment. Here, the authors use a multigene next-generation sequencing panel to identify genomic differences in Nigerian CRCs compared to those from TCGA and MSKCC cohorts.
format article
author Olusegun Isaac Alatise
Gregory C. Knapp
Avinash Sharma
Walid K. Chatila
Olukayode A. Arowolo
Olalekan Olasehinde
Olusola C. Famurewa
Adeleye D. Omisore
Akinwumi O. Komolafe
Olaejinrinde O. Olaofe
Aba I. Katung
David E. Ibikunle
Adedeji A. Egberongbe
Samuel A. Olatoke
Sulaiman O. Agodirin
Olusola A. Adesiyun
Ademola Adeyeye
Oladapo A. Kolawole
Akinwumi O. Olakanmi
Kanika Arora
Jeremy Constable
Ronak Shah
Azfar Basunia
Brooke Sylvester
Chao Wu
Martin R. Weiser
Ken Seier
Mithat Gonen
Zsofia K. Stadler
Yelena Kemel
Efsevia Vakiani
Michael F. Berger
Timothy A. Chan
David B. Solit
Jinru Shia
Francisco Sanchez-Vega
Nikolaus Schultz
Murray Brennan
J. Joshua Smith
T. Peter Kingham
author_facet Olusegun Isaac Alatise
Gregory C. Knapp
Avinash Sharma
Walid K. Chatila
Olukayode A. Arowolo
Olalekan Olasehinde
Olusola C. Famurewa
Adeleye D. Omisore
Akinwumi O. Komolafe
Olaejinrinde O. Olaofe
Aba I. Katung
David E. Ibikunle
Adedeji A. Egberongbe
Samuel A. Olatoke
Sulaiman O. Agodirin
Olusola A. Adesiyun
Ademola Adeyeye
Oladapo A. Kolawole
Akinwumi O. Olakanmi
Kanika Arora
Jeremy Constable
Ronak Shah
Azfar Basunia
Brooke Sylvester
Chao Wu
Martin R. Weiser
Ken Seier
Mithat Gonen
Zsofia K. Stadler
Yelena Kemel
Efsevia Vakiani
Michael F. Berger
Timothy A. Chan
David B. Solit
Jinru Shia
Francisco Sanchez-Vega
Nikolaus Schultz
Murray Brennan
J. Joshua Smith
T. Peter Kingham
author_sort Olusegun Isaac Alatise
title Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
title_short Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
title_full Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
title_fullStr Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
title_full_unstemmed Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
title_sort molecular and phenotypic profiling of colorectal cancer patients in west africa reveals biological insights
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/939275ce40494796b17543b64bb2bcce
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