Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS

Objectives: This study aims to describe and classify the drugs prescribed for coinfected patients treated at a reference hospital. Methods: A retrospective cross-sectional study with analysis of information contained in a database prepared in an earlier study The Anatomical Therapeutic Chemical (AT...

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Autores principales:	Isabella S. LOBO, Wânia S. CARVALHO, Natália H. RESENDE
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
Materias:	tuberculosis HIV coinfection opportunistic infections drug utilization Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/939816bb104f499ab7003ad59325472a
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spelling	oai:doaj.org-article:939816bb104f499ab7003ad59325472a2021-11-28T02:45:14ZDrug utilization research in coinfected patients with tuberculosis and HIV/AIDS10.30968/rbfhss.2020.111.04202179-59242316-7750https://doaj.org/article/939816bb104f499ab7003ad59325472a2020-07-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/420https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Objectives: This study aims to describe and classify the drugs prescribed for coinfected patients treated at a reference hospital. Methods: A retrospective cross-sectional study with analysis of information contained in a database prepared in an earlier study The Anatomical Therapeutic Chemical (ATC) classification system was used to classify the prescribed drugs. Results: Eighty-one coinfected individuals participated in the study, with a mean age of 40 years old and numerous comorbidities. A total of 147 drugs were found and, when the frequency of prescription was evaluated, the most used therapeutic groups were anti-infectious, considering the large number of opportunistic infections (OIs) presented by coinfected patients, followed by feeding tract drugs used to treat adverse drug reactions. We could observe that 73% of the evaluated population had a CD4+ T lymphocyte count <200 cells/mm3 and a high viral load, indicating advanced immunodeficiency. Conclusion: It is necessary to develop strategies aimed at coinfected patients, such as specialized care, early diagnosis and appropriate treatment of coinfection. It is also important to carry out more studies on the use of drugs among coinfected patients to create actions directed to this population that may contribute to the rational use of drugs. Isabella S. LOBOWânia S. CARVALHONatália H. RESENDESociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticletuberculosisHIVcoinfectionopportunistic infectionsdrug utilizationPublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 11, Iss 1 (2020)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	tuberculosis HIV coinfection opportunistic infections drug utilization Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	tuberculosis HIV coinfection opportunistic infections drug utilization Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Isabella S. LOBO Wânia S. CARVALHO Natália H. RESENDE Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS
description	Objectives: This study aims to describe and classify the drugs prescribed for coinfected patients treated at a reference hospital. Methods: A retrospective cross-sectional study with analysis of information contained in a database prepared in an earlier study The Anatomical Therapeutic Chemical (ATC) classification system was used to classify the prescribed drugs. Results: Eighty-one coinfected individuals participated in the study, with a mean age of 40 years old and numerous comorbidities. A total of 147 drugs were found and, when the frequency of prescription was evaluated, the most used therapeutic groups were anti-infectious, considering the large number of opportunistic infections (OIs) presented by coinfected patients, followed by feeding tract drugs used to treat adverse drug reactions. We could observe that 73% of the evaluated population had a CD4+ T lymphocyte count <200 cells/mm3 and a high viral load, indicating advanced immunodeficiency. Conclusion: It is necessary to develop strategies aimed at coinfected patients, such as specialized care, early diagnosis and appropriate treatment of coinfection. It is also important to carry out more studies on the use of drugs among coinfected patients to create actions directed to this population that may contribute to the rational use of drugs.
format	article
author	Isabella S. LOBO Wânia S. CARVALHO Natália H. RESENDE
author_facet	Isabella S. LOBO Wânia S. CARVALHO Natália H. RESENDE
author_sort	Isabella S. LOBO
title	Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS
title_short	Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS
title_full	Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS
title_fullStr	Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS
title_full_unstemmed	Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS
title_sort	drug utilization research in coinfected patients with tuberculosis and hiv/aids
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2020
url	https://doaj.org/article/939816bb104f499ab7003ad59325472a
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Drug utilization research in coinfected patients with tuberculosis and HIV/AIDS

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